The Portland Trail Blazers (5-5) visit the New Orleans Pelicans (2-8) Wednesday. Tip-off from Smoothie King Center in New Orleans, Louisiana, is set for 8 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Trail Blazers vs. Pelicans odds and make our expert NBA picks and predictions for the best bets.

2024-25 season series: Portland won 3-1

Portland lost 115-112 to the Orlando Magic Monday, failing to cover as a 2-point road underdog with the Under (235) hitting. G Shaedon Sharpe (31 points) and F Deni Avdija (27) combined for 58 points, but only 2 other Blazers finished in double figures. The Blazers were outrebounded 50-38.

New Orleans was routed 121-98 by the Phoenix Suns Monday, failing to cover as an 8.5-point road underdog with the Under (227) cashing. Suns G Grayson Allen dropped 42 points and hit 10 three-pointers — a franchise record. The Pelicans allowed Phoenix to shoot 50% from the field and 44.2% from deep.

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Trail Blazers at Pelicans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:29 p.m. ET.

Moneyline (ML): Trail Blazers -350 (bet $350 to win $100) | Pelicans +275 (bet $100 to win $275)Against the spread (ATS): Trail Blazers -8.5 (-105) | Pelicans +8.5 (-115)Over/Under (O/U): 229.5 (O: -115 | U: -105)Trail Blazers at Pelicans key injuries

Trail Blazers

G Scoot Henderson (hamstring) outG Damian Lillard (Achilles) outF Matisse Thybulle (thumb) out

Pelicans

G Dejounte Murray (Achilles) outG Jordan Poole (quad) outF Zion Williamson (hamstring) out

For most recent updates: Official NBA injury report.

Pelicans at Trail Blazers picks and predictionsPrediction

Trail Blazers 111, Pelicans 97

PASS.

The Blazers are the better team, and with Williamson out, the Pelicans will have no chance of pulling off the upset. However, the Blazers are not worth the risk as -350 favorites, so pass and bet the spread and/or total instead.

BET TRAIL BLAZERS -8.5 (-105).

The Pelicans rank in the bottom 4 in both offensive and defensive rating. With Poole and Williamson both out, this already underperforming team will look even worse. On the other side, the Blazers have the eighth-best scoring offense and 11th-best defensive rating in the NBA, while also forcing the most turnovers per game (19).

Portland is also 5-0 ATS in its last 5 matchups against New Orleans.

BET UNDER 229.5 (-105).

New Orleans scores just 108 points per game (PPG) on 43.3% shooting from the field, ranking second-worst in the NBA in both, so the Pelicans likely won’t even reach 100 points in this matchup due to injuries. On the other side, the Blazers put up 120.6 PPG and will likely score at least 25 points off turnovers, but their offense isn’t powerful enough to make the Over a real threat.

The Under is 3-1 in New Orleans’ last 4 games and 4-1 in the last 5 matchups between these squads.

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