A pair of the NBA’s top players will be on show when Cade Cunningham (27.1 points per game, 14th in league) and the Detroit Pistons (15-2) travel to face Jaylen Brown (27.9, 10th) and the Boston Celtics (9-8) on Wednesday, November 26, 2025 at 5 p.m. ET on ESPN, NBCS-BOS, and FDSDET.
The Pistons take on the Celtics. The Pistons are favored by 3.5 points against the Celtics. The matchup’s point total is set at 228.5.
Pistons vs. Celtics betting odds
NBA odds courtesy of BetMGM Sportsbook. Odds updated Tuesday at 7:29 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread: Detroit -3.5Total: 228.5Moneyline: Detroit -163, Boston +138
Pistons at Celtics odds, spread, & morePredictionPick ATS: Celtics (+ 3.5)Pick OU:
Over (228.5)Prediction:
Celtics 115 – Pistons 114MoneylineThe Pistons have won 92.3% of the games this season when they were the moneyline favorite (12-1).Detroit has won all nine games it played as a moneyline favorite with odds of -163 or shorter.Based on this contest’s moneyline, the Pistons have an implied win probability of 62.0%.The Celtics have been underdogs in six games this season and won two (33.3%) of those contests.This season, Boston has won one of its three games when it is the underdog by at least +138 on the moneyline.Bookmakers have implied with the moneyline set for this matchup that the Celtics have a 42.0% chance to win.Against the spreadThe 119.6 points per game the Pistons score are 9.6 more points than the Celtics allow (110).Detroit is 12-4 against the spread and 15-1 overall when scoring more than 110 points.Boston has put together a 6-3 ATS record and a 7-2 overall record in games it scores more than 112.6 points.Detroit is 10-1 against the spread and 11-0 overall when it gives up fewer than 114.6 points.The Pistons are at the eighth spot in the NBA’s scoring charts (119.6 PPG), while the Celtics allow the second-fewest points per game (110) in the league.The 22nd-ranked scoring NBA team (114.6 PPG) is Boston, while the Detroit squad ranks fifth in the league defensively (112.6 PPG).The Pistons have totaled 119 more points than their opponents this season (seven per game on average), and the Celtics have scored 79 more points than their opponents (4.6 per game).Over/UnderThe average implied total for Detroit this year is 118.5 points, 2.5 more points than its implied total of 116 points in Wednesday’s game.So far this season, Detroit has totaled more than 116 points in a game 10 times.Boston’s average implied point total on the season (117.3 points) is 4.3 points higher than its implied total in this matchup (113 points).How to watch Pistons vs. Celtics