The San Antonio Spurs are on the road on Wednesday night as they travel to take on the Portland Trail Blazers in a Western Conference matchup as part of NBA Cup group play.

San Antonio enters Wednesday’s game with an 11-5 record after losing on the road to the Phoenix Suns on Sunday night.

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San Antonio Spurs guard De'Aaron Fox (4)© Petre Thomas-Imagn Images

San Antonio Spurs guard De’Aaron Fox (4)© Petre Thomas-Imagn Images

In Sunday’s loss to the Suns, De’Aaron Fox led the way for the Spurs as he recorded 26 points and five rebounds while Devin Vassell added 17 points and four rebounds of his own.

Now San Antonio will try to bounce back on Wednesday night on the road in a tough matchup against the Trail Blazers.

On the other side, Portland enters Wednesday’s contest with an 8-10 record after losing on the road to the Milwaukee Bucks on Monday night.

Portland Trail Blazers forward Jerami Grant (9)© Mike Watters-Imagn Images

Portland Trail Blazers forward Jerami Grant (9)© Mike Watters-Imagn Images

Jerami Grant led the way for the Trail Blazers in Monday’s loss as he ended the game with 35 points, four rebounds and four assists while Deni Avdija recorded 22 points, four rebounds and five assists.

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While both teams are looking to pick up a victory in Wednesday night’s matchup, both squads may be without multiple key players due to injuries.

Spurs Injury Report, Will Victor Wembanyama, Dylan Harper Play?

For the Spurs, they have four players listed on their injury report for Wednesday’s game, including superstar center Victor Wembanyama.

San Antonio Spurs forward Victor Wembanyama (1)Daniel Dunn-Imagn Images

San Antonio Spurs forward Victor Wembanyama (1)Daniel Dunn-Imagn Images

San Antonio has ruled out Wembanyama due to a left calf strain as he will miss his fifth consecutive contest.

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With Wembanyama still sidelined, Luke Kornet will likely draw another start in his place while Kelly Olynyk could continue to have a larger role off the bench.

San Antonio Spurs guard Dylan Harper (2)Scott Wachter-Imagn Images

San Antonio Spurs guard Dylan Harper (2)Scott Wachter-Imagn Images

The Spurs have also ruled out Jordan McLaughlin and Stephon Castle while rookie Dylan Harper has been upgraded to questionable due to a left calf strain that has sidelined him the last 10 games.

Trail Blazers Injury Report, Will Shaedon Sharpe, Jrue Holiday Play?

On the other side, the Trail Blazers have six players listed on their injury report, including Shaedon Sharpe.

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Portland Trail Blazers guard Shaedon Sharpe (17)Kevin Jairaj-Imagn Images

Portland Trail Blazers guard Shaedon Sharpe (17)Kevin Jairaj-Imagn Images

Portland has listed Sharpe as questionable for Wednesday’s game due to a right calf strain and he is in danger of missing his fifth consecutive contest.

If Sharpe is sidelined once again on Wednesday, Sidy Cissoko and Caleb Love could be in line for larger roles.

Portland Trail Blazers guard Jrue Holiday (5)Rob Gray-Imagn Images

Portland Trail Blazers guard Jrue Holiday (5)Rob Gray-Imagn Images

The Trail Blazers have ruled out Jrue Holiday, Scoot Henderson, Blake Wesley, Matisse Thybulle and Damian Lillard as they all continue to recover from injuries.

Fans can catch Wednesday night’s matchup between the Spurs and Trail Blazers from Portland at 10:00 p.m. EST.

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This story was originally published by Athlon Sports on Nov 26, 2025, where it first appeared in the NBA section. Add Athlon Sports as a Preferred Source by clicking here.