The Philadelphia 76ers (14-11) will look to Tyrese Maxey (third in the league scoring 31.5 points per game) when they attempt to defeat Jalen Brunson (seventh in the NBA with 28.7 PPG) and the New York Knicks (19-7) on Friday, December 19, 2025 at Madison Square Garden. The 76ers are 5.5-point road underdogs in the game, which tips at 7 p.m. ET on Amazon Prime Video and MSG. The over/under in the matchup is set at 229.5.
In its most recent game, Philadelphia lost to the Hawks on Sunday, 120-117. Its high scorer was Paul George with 35 points.
76ers vs. Knicks betting information
NBA odds courtesy of BetMGM Sportsbook. Odds updated Friday at 1:25 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread: New York -5.5Moneyline: New York -220, Philadelphia +180Total: 229.5 points76ers betting insightsThe 76ers are 14-11-0 against the spread this season.When they have played as at least 5.5-point underdogs this season, the 76ers are 1-1 against the spread.The 76ers have gone over in 12 of their 25 games with a set total (48%).76ers key playersTyrese Maxey: 31.5 PTS, 7.2 AST, 1.7 STL, 46.7 FG%, 39.1 3PT% (84-for-215)Quentin Grimes: 16.2 PTS, 44 FG%, 36.9 3PT% (58-for-157)VJ Edgecombe: 15.2 PTS, 1.3 STL, 42.1 FG%, 38.8 3PT% (45-for-116)Andre Drummond: 7.3 PTS, 9.4 REB, 53 FG%, 36.7 3PT% (11-for-30)Joel Embiid: 20.5 PTS, 1.3 BLK, 42.1 FG%, 22.6 3PT% (12-for-53)76ers vs. Knicks game info