The San Antonio Spurs and Toronto Raptors, two teams in the thick of their respective conference playoff races, meet on Wednesday night in Canada. It’s the lone trip north of the border for San Antonio this season. The clash tips at 7:30 p.m. ET.
The Spurs are a perfect 9-0 in February and sit a season-high 25 games over .500 and in second place in the Western Conference. The Raptors just lost to the only team above the Spurs in the West, the defending champion Thunder. Toronto is in fifth place in the Eastern Conference, two games ahead of the 76ers.
Below, we’ll break down our Spurs vs. Raptors prediction, spread, and NBA picks for Wednesday’s game. Make your picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals.
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Spurs vs. Raptors Prediction, Spread, NBA Picks for February 25
The Spurs and Raptors meet for the second time this season, with San Antonio winning by 18 back in October. Overall, the Spurs lead the all-time series 39-20, with wins in each of the last four games, including a season sweep last year.
Spurs vs. Raptors Over/Under, Spread
The Spurs enter the game as 6.5-point favorites, returning a 1.33x payout on PrizePicks Team Picks if they win.
The Raptors are the underdogs with a 3.22x payout if they win, via PrizePicks Team Picks.
Spread: San Antonio Spurs -6.5Over/Under: 228.5Game Winner Payout: Spurs 1.33x | Raptors 3.22x
Team Picks data is live at the time of writing and is subject to change.
Spurs vs. Raptors Prediction on Spread
I would be more than OK with a Detroit Pistons / San Antonio Spurs finals.
Gives me deja vu and brings me back to my playing days, when those two teams were built…sorta like these ones are.
Guard play, bigs. Skill, aggression. Offense and defense.
Love it!
— Michael Redd (@MichaelRedd_) February 24, 2026
The Spurs are a 6.5-point favorites tonight, the tenth time in the last 11 games they are laying points.
The Spurs are 32-24-2 against the spread this season, the third-best record against the spread in the league.San Antonio is 8-1 vs. the number during the current nine-game winning streak. As a favorite, the Spurs are 20-18-2 ATS this season as a favorite, including a 7-7-1 record as a road favorite. San Antonio has played 34 of 58 games (including the NBA Cup Final) under the posted number. The 34 unders are the fourth most in the NBA. The Spurs are led by their defense, which is third in the league in defensive rating (110.5), fourth in opponents’ FG pct (45.3), and third in rebounds (46.7).The Raptors also play solid defense, landing sixth in defensive rating (111.8) and ninth in opponents’ FG pct (46.0).The Raptors are 29-29 against the spread this season, including covers in five of the last seven games. They not cover Tuesday night at home against the Thunder.Toronto is 14-10 against the number as an underdog this season, including 4-5 ATS as a home dog.Spurs vs. Raptors Injury Report
Let’s dive into the full Spurs vs. Raptors injury report for Wednesday, via NBA.com
Spurs Injury Report C Mason Plumlee (conditioning) – OUTRaptors Injury ReportNot posted as of publicationSpurs vs. Raptors Picks for PrizePicks Today: Wednesday, February 25
Here are two Spurs vs. Raptors picks to target for Wednesday, February 25 on PrizePicks. Player stat projections via PrizePicks are headlined by Spurs C Victor Wembanyama and Raptors F Brandon Ingram
Spurs F Victor Wembanyama Projection vs. Raptors: 38.5 Points+Rebounds+Assists
Honestly not sure I’ve ever seen this before, but it’s a great example of Victor Wembanyama’s unique rim protection.
Duncan Robinson gets a step and Wemby turns to negate the lob to Jalen Duren, turns his back on Duncan, only to STILL contest the floater.pic.twitter.com/llEtbTDFku
— Hot Hand Theory (@HotHandTheory) February 24, 2026 Spurs F Victor Wembanyama has reached his Points+Rebounds+Assists (PRA) projection in four of his last five and six of his last eight games. In the two games he did not hit the PRA, he played less than 30 minutes due to blowouts. The French big man is averaging 11.3 rebounds per game this season, fifth in the NBA, and 24.2 points per game, which is 22nd. During the Spurs’ current nine-game winning streak, Wemby averaged 24.9 points, 12.0 rebounds, and 3.4 assists per game (40.3 PRA) Raptors F Brandon Ingram Projection vs. Spurs: 21.5 PointsRaptors F Brandon Ingram has failed to reach his points projection in four of the past five games. The difference between hitting his points prop or not over those five games was his 3’s, where he is 5-15 from the field. The 33% is 4 points below his 36.9% season clip.Ingram has scored 20+ points in 35 of 55 games this season, which includes eight games of 30+. In the one game vs. the Spurs earlier this season, Ingram struggled from the field, only hitting 5-of-11 shots, and going 0-3 from beyond the arc, finishing with 14 points.
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Make Spurs vs. Raptors NBA Picks on PrizePicks
Can the Spurs continue their winning streak and stay within striking distance of the Thunder at the top of the Western Conference? Or will the Raptors rebound from their loss to the top-seeded Thunder and knock off the team with the second-best record in the West?
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