AP Photo/Jae C. Hong)

Tonight at the Intuit Dome in Inglewood, CA, the Minnesota Timberwolves (37-22) face the LA Clippers (27-30) in a Western Conference matchup that tips off at 10 p.m. ET on Prime Video.

After being one of the hottest teams in the NBA during December and January, the Clippers have cooled down in February with a 5-5 record. 

The Timberwolves are on a good run at the moment, winning four of their last five, scoring more than 120 points in each of those victories.

Let’s look at the Timberwolves vs. Clippers prediction, spread, and NBA picks for Thursday, February 26. Make your picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners and totals.

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Timberwolves vs. Clippers Prediction, Spread, NBA Picks for 2/26

The season series is tied 1-1, with the Timberwolves winning 109-106 on December 6, 2025, and the Clippers winning 115-96 on February 6, 2026.

The Clippers seemed finished early in the season after starting with a  6-21 record, but they turned it around, and since December 20, have gone 20-9, the third-best record in the NBA. Their success during this period is partly attributable to a stellar defense that ranks fourth in points allowed per game (108.5) and third in opponents’ made field goals (39.6). 

However, that slow start could cost them a playoff berth, as they are currently the tenth seed, the final spot in the Play-In Tournament.

The Timberwolves are firmly in the sixth seed, but they are within striking distance of fourth, giving them home-court advantage in the first round. It makes every game important for Minnesota, which tasted postseason success last season by reaching the Western Conference Finals.

Controlling this offense is tough, as they’re one of the league’s best shooting teams, ranking third this season with 119.6 points per game and fourth with a 48.4% field goal percentage.

Timberwolves vs. Clippers Prediction, Spread, Over/Under

The Timberwolves enter this matchup as a 5.5-point favorite, returning a 1.44x payout on PrizePicks Team Picks if they win outright.

The Clippers are home underdogs with a 2.7x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 34 states.

Spread: Minnesota Timberwolves -5.5Over/Under: 225.5Game Winner Payout: Timberwolves 1.44x | Clippers 2.7x

Team Picks data is live at the time of writing and is subject to change.

Timberwolves vs. Clippers Spread, Over/Under

Here are some key facts and figures the check outbefore locking in your Timberwolves vs. Clippers prediction on spread or over/under for Thursday, February 26 on PrizePicks.

The Clippers have covered five straight games as the underdog.The Timberwolves have failed to cover the spread in seven of their last nine games.Los Angeles struggles to cover at home with a 12-14 record against the spread.Minnesota is only 12-16 against the spread on the road.The Clippers struggle to cover after a loss, going just 13-16 ATS in that situation.The T-Wolves are 19-28 when set as the favorite.Timberwolves vs. Clippers Injury Report

Let’s dive into the full Timberwolves vs. Clippers injury report for Thursday, via NBA.com.

Timberwolves Injury Report Clippers Injury Report PF John Collins (head/neck) – QuestionableG Darius Garland (toe) – OUTG Kawhi Leonard (ankle) – QuestionableTimberwolves vs. Clippers Picks for PrizePicks Today: 2/26/26

Here are two top Timberwolves vs. Clippers PrizePicks picks to target on Thursday, featuring Clippers G Kawhi Leonard and Timberwolves C Naz Reid.

Clippers G Kawhi Leonard Projection vs. Timberwolves: 29.5 PointsLeonard has been one of the league’s top scorers over the last few weeks, ranking fourth in points per game since December 18 (30.1).The seven-time All-Star’s 37 points against the Timberwolves on February 8 were his fifth-highest total of the season.The former San Diego State star has 30+ points in four of his last seven games.The 2011 first-round pick’s 38.4% usage rate against Minnesota is the highest among opponents he’s faced at least two times this year.Timberwolves C Naz Reid Projection vs. Clippers: 8.5 Rebs+AstReid has more than 8 reb+ast in 31 of the last 58 games during the 2025-26 season.Reid has more than 8 reb+ast in five of the last eight road games.Reid led the Timberwolves in rebounds and assists against the Clippers on February 8, and has led the team in rebounds in both games vs. Los Angeles this season.Reid’s 8.5 assisted points per 75 possessions ranks in the 78th percentile according to databllr.

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Make Timberwolves vs. Clippers NBA Picks on PrizePicks

You can make your Timberwolves vs. Clippers picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 34 states. 

Stick around with the Playbook for continued NBA predictions, picks, and news every day until the 2026 NBA Finals.

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