March 13, 2026, 10:40 a.m. ET

The Memphis Grizzlies (23-42) and Detroit Pistons (47-18) meet at Little Caesars Arena in Detroit, Michigan, on Friday. Tip-off is set for 7:30 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Grizzlies vs. Pistons odds and make our expert NBA picks and predictions for the best bets.

Season series: Pistons lead 1-0

Memphis was handed a 120-112 loss by the Dallas Mavericks on Thursday, failing to cover as a 5.5-point home underdog with the Under (238.5) hitting. The Mavs dominated the Grizzlies 60-38 on the glass and 64-42 in paint scoring. The Grizzlies have lost 6 straight and have allowed at least 120 points in each of their last 5 losses.

Detroit embarrassed the Philadelphia 76ers 131-109 Thursday, covering as a 15.5-point home favorite with the Over (224.5) cashing. G Duncan Robinson scored 19 points to lead Detroit, finishing as 1 of 7 guys to score in double figures in the win. The Pistons have won back-to-back games by over 20 points, scoring 131 or more points in both.

The Pistons handed the Grizzlies a 114-106 loss on Nov. 3 while covering as a 4-point road favorite with the Under (235.5) cashing. G Cade Cunningham scored 33 points and F/C Isaiah Stewart finished with 26 points and 14 boards in the win. The Grizzlies turned the ball over 20 times.

Watch the NBA on Fubo!Grizzlies at Pistons odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 10:30 a.m. ET.

Moneyline (ML): Grizzlies +750 (bet $100 to win $750) | Pistons -1200 (bet $1,200 to win $100)Against the spread (ATS): Grizzlies +15.5 (-110) | Pistons -15.5 (-110)Over/Under (O/U): 231.5 (O: -115 | U: -105)Grizzlies at Pistons key injuries

Grizzlies

(Not yet submitted — below was for Thursday’s game)

F Santi Aldama (knee) outG Kentavious Caldwell-Pope (finger) outC Brandon Clarke (calf) outG Walter Clayton Jr. (ankle) doubtfulF/G Cedric Coward (knee) outC Zach Edey (ankle) outG Ty Jerome (calf) doubtfulG Ja Morant (elbow) outG Scotty Pippen Jr. (toe) outG Cam Spencer (back) out

Pistons

(Not yet submitted — below was for Thursday’s game)

G Caris LeVert (wrist) outF Ausar Thompson (ankle) out

For most recent updates: Official NBA injury report.

Grizzlies at Pistons picks and predictionsPrediction

Pistons 121, Grizzlies 112

PASS.

The Pistons will easily win and cover here as -1200 favorites, but they are not worth the risk of betting on as such heavy favorites. Pass and bet on the safer spread and/or Over/Under bets instead.

BET GRIZZLIES +15.5 (-110).

Memphis has covered the spread in 9 of its last 10 matchups against the Pistons, including in 5 straight at Detroit. The Grizzlies are also 5-3 ATS in their last 8 games while the Pistons are just 3-7 ATS in their last 10 overall.

The Grizzlies are trying to lose games, but they’ll likely keep this one within 16 points while doing so.

LEAN OVER 231.5 (-115).

The Over has hit in 4 of Memphis’ last 5 games overall and in each of its last 2 road games. For Detroit, the Over is 4-1 in its last 5 wins. The Over has also hit in 3 of the last 5 matchups between these squads that took place in Detroit.

Memphis has allowed at least 120 points in 5 straight losses, and the Pistons have put up at least 120 points in 4 of their last 5 wins, so the Over is the safer bet here.

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