March 19, 2026, 11:15 a.m. ET

The Cleveland Cavaliers (42-27) and Chicago Bulls (28-41) meet Thursday at United Center in Chicago, Illinois. Tip-off is scheduled for 8 p.m. ET. Let’s analyze NBA odds around the Cavaliers vs. Bulls odds and make our expert NBA picks and predictions for the best bets.

Season series: Bulls lead 2-1; Chicago won 127-111 on Dec. 17, the only previous meeting this season at United Center. The Bulls covered as a 5.5-point underdog (+180 ML) as the Under (242.5) cashed. Chicago is 3-0 against the spread (ATS) against Cleveland this season while the Over is 2-1.

Cleveland picked up a 123-116 victory in Milwaukee on Tuesday buy failed to cover as a 12.5-point favorite as the Over (226.5) cashed. G James Harden and C Evan Mobley went for 27 points apiece, with Mobley adding 15 rebounds and 3 blocks. The Cavs have alternated wins and losses in the past 7 outings and are 2-4-1 ATS that span. The Over has cashed in 4 in a row.

Chicago was crushed 139-109 as a 7.5-point home underdog with the Over (237.5) cashing Wednesday against Toronto. F Matas Buzelis went for 19 points, 7 rebounds, 2 steals and a block while hitting a trio of 3-pointers. The Bulls have dropped 3 of their past 4 games but are still a respectable 6-3 ATS across their past 9 outings. The Under is 9-3 in Chicago’s last 12 games.

Watch the NBA on Fubo!Cavaliers at Bulls odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 11:10 a.m. ET.

Moneyline (ML): Cavaliers -800 (bet $800 to win $100) | Bulls +550 (bet $100 to win $550)Against the spread: Cavaliers -12.5 (-118) | Bulls +12.5 (-102)Over/Under (O/U): 240.5 (O: -115 | U: -105)Cavaliers at Bulls key injuries

Cavaliers

F Jarrett Allen (knee) outG Craig Porter Jr. (groin) outG Tyrese Proctor (quadriceps) out

Bulls

(Not yet submitted — below was for Wednesday’s game)

G Jaden Ivey (knee) outG Anfernee Simons (wrist) out

For most recent updates: Official NBA injury report.

Cavaliers at Bulls picks and predictionsPrediction

Cavaliers 124, Bulls 113

The Cavaliers (-800) will cost you 8 times your potential return, and that’s way too much risk for a straight-up play, or as part of a multi-leg parlay. There is just no value backing such a strong favorite, especially on the road.

AVOID.

It’s difficult to trust a BULLS +12.5 (-102) which was crushed by 30 points at home on Wednesday. However, prior to that, Chicago won 132-107 against Memphis on Monday. So, who is going to show up in red and black?

The Cavaliers have lost 2 of 3 games outright to the Bulls, who seem to be the kryptonite for Cleveland. The Cavs are just 1-4-1 ATS in the past 6 games, and 4-8-1 ATS across the previous 13 outings. So, take Chicago, but go lightly.

UNDER 240.5 (-105) is the lean, but go with a half-unit play at most.

The Over is 4-0 in the past 4 games for Cleveland, but this is a very high number. We saw a similar total of 242.5 in mid-December in Chicago, and the total went Under. The Under is 9-3 in the past 12 games for the Bulls, too, so trust it, just go lightly.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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