April 6, 2026, 12:08 p.m. ET

The Portland Trail Blazers (40-38) visit the Denver Nuggets (50-28) at Ball Arena Monday. Tip-off from Denver, Colorado, is set for 9 p.m. ET. Let’s analyze NBA odds around the Trail Blazers vs. Nuggets odds and make our expert NBA picks and predictions for the best bets.

Season series: Nuggets lead 2-1

Portland beat the New Orleans Pelicans 118-106 Thursday to cover as a 6-point home favorite as the Under (234.5) cashed. G Jrue Holiday led the Blazers with 27 points, G Deni Avdija had 26 and F Toumani Camara had 23. The Blazers are locked into a play-in game and are the No. 9 seed in the Western Conference, tied with the LA Clippers who hold the tiebreaker for the 8 seed.

Denver escaped with a 136-134 OT win over the San Antonio Spurs Saturday while covering as a 1.5-point home underdog as the Over (243.5) was smashed. C Nikola Jokic went off for 40 points, 13 assists, and 8 rebounds. The Nuggets have clinched a playoff spot and are the 4 seed in the West, tied with the 3-seed Los Angeles Lakers and 1 game ahead of the 5-seed Houton Rockets.

The Nuggets handed the Blazers a 128-112 loss on March 22 while covering as 8-point home favorites as the Over (237.5) hit. Denver led 27-9 in transition scoring and 54-46 in paint scoring in the win. The Nuggets have come away with back-to-back wins over Portland, winning both games by over 15 points.

Watch the NBA on Fubo!Trail Blazers at Nuggets odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:01 p.m. ET.

Moneyline (ML): Trail Blazers +260 (bet $100 to win $260) | Nuggets -325 (bet $325 to win $100)Against the spread (ATS): Trail Blazers +7.5 (-105) | Nuggets -7.5 (-115)Over/Under (O/U): 238.5 (O: -105 | U: -115)Trail Blazers at Nuggets key injuries

Trail Blazers

F Jerami Grant (calf) outG Vit Krejci (calf) outG Damian Lillard (achilles) outG Shaedon Sharpe (leg) out

Nuggets

G/F Bruce Brown (ankle) probableC Zeke Nnaji (hip) questionableF Peyton Watson (hamstring) out

For most recent updates: Official NBA injury report.

Trail Blazers at Nuggets picks and predictionsPrediction

Nuggets 128, Trail Blazers 115

PASS.

The Nuggets are the much better team, so they will have no problem covering here as (-325) favorites. However, no team favored so heavily is worth the risk of backing on the ML, so pass here and bet on the spread and/or total instead.

LEAN NUGGETS -7.5 (-115).

Denver has covered the spread in 2 of its last 3 home games. Against Portland, the Nuggets have covered ATS in back-to-back games and are 3-0 ATS in their last 3 matchups in Denver.

With the Nuggets back to full health, they will be using every game as an opportunity to build confidence heading into the playoffs, so look for Denver to come out hot and not let up in this one.

This is a lean because the Blazers are 7-3 ATS in their last 10 games.

BET OVER 238.5 (-105).

The Over has hit in 4 of Denver’s last 5 home games and is 48-30 for the Nuggets this season. For Portland, the Over is 40-38. The Over has also hit in 8 of the last 10 matchups between these squads, including in all of the last 3 matchups in Denver and in all of Denver’s last 6 wins over Portland.

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