April 23, 2026, 4:06 p.m. ET

The Cleveland Cavaliers and Toronto Raptors meet Thursday for Game 3 of their first-round Eastern Conference playoff series. Tip-off from Scotiabank Arena in Toronto, Ontario, is scheduled for 8 p.m. ET (Prime Video). Let’s analyze NBA odds around the Cavaliers vs. Raptors odds and make our expert NBA picks and predictions for the best bets.

Best-of-7 series: Cavaliers lead 2-0

The Cavaliers posted a 115-105 win as 9.5-point favorites in Game 2, cashing the Under (222.5). Both barely cashed, but they cashed nonetheless. The Cavs are 2-0 straight up (SU) and against the spread (ATS) in the first 2 games of the series after going 0-3 SU/ATS against Toronto in the regular season.

Raptors F Scottie Barnes had 26 points with 5 assists, 4 rebounds, 2 steals, a block and a 3-pointer in the losing effort in Game 2. G RJ Barrett continues his solid series, chipping in with 22 points on 10-of-13 shooting. He is averaging 23.0 PPG, 5.5 RPG and 4.0 APG in the series.

Cavaliers G Donovan Mitchell went for 30 points with 7 rebounds, 5 assists, 4 3-pointers and a steal in 37 minutes in Game 2 while G James Harden was good for 28 points with 5 steals and 3 triples. F Evan Mobley added 25 points, 8 rebounds, 2 assists and a block, too, while hitting 11 of 13 from the field.

Cleveland has picked up wins in 13 of its past 16 games, while going 5-1 ATS in the past 6 outings. The Over has cashed in 4 of the past 6 outings. Toronto has dropped 6 in a row SU and ATS as an underdog.

Watch the NBA on Fubo!Cavaliers at Raptors odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:50 p.m. ET.

Moneyline (ML): Cavaliers -150 (bet $150 to win $100) | Raptors +125 (bet $100 to win $125)Against the spread: Cavaliers -2.5 (-110) | Raptors +2.5 (-110)Over/Under (O/U): 222.5 (O: -105 | U: -115)Cavaliers at Raptors key injuries

Cavaliers

C Thomas Bryant (calf) probable

Raptors

PG Immanuel Quickley (hamstring) questionableSG Ja’Kobe Walter (illness) questionable

For most recent updates: Official NBA injury report.

Cavaliers at Raptors picks and predictionsPrediction

Raptors 115, Cavaliers 111

The RAPTORS (+125) are worth a look in Game 3, as they look to make a series of it. Toronto will either win Game 3 or likely get swept. There isn’t a lot of gray area.

Toronto has lost the past 5 games against playoff teams, but it has won the past 3 home games against teams in the playoff field, so that’s good news.

Toronto +2.5 (-110) makes very little sense to play. Whenever you have an underdog catching 2.5 or fewer points, don’t pay up for a tiny amount of insurance, just play the moneyline, instead.

On the flip side, if you like the Cavaliers -2.5 (-110), lay the points instead of playing the moneyline.

AVOID.

OVER 222.5 (-105) is worth a look for Game 3.

The total split in the first 2 games in Cleveland, with the Cavs averaging 120.5 PPG and the Raps averaging 109.0. Let’s go high on the total, and all the teams need to do is hit their series averages.

The Over has cashed in 4 of the past 5 home games for Toronto, while Cleveland has hit the high in 3 of the past 4 road outings.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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