An Eastern Conference matchup tips off the Wednesday NBA schedule as the Charlotte Hornets host the Cleveland Cavaliers. Charlotte is 16-27 overall, but coming off a 3-2 West Coast trip that included dominant wins over the Lakers and Nuggets. The Cavs are 24-20, though they were blown out 136-104 in a cross-conference showdown against the Thunder on Monday. Darius Garland (toe) and Sam Merrill (hand) remain out for Cleveland.\u00a0<\/p>\n
Tipoff is at 7 p.m. ET from the Spectrum Center in Charlotte. The Cavs are 2.5-point road favorites in the latest Cavaliers vs. Hornets odds, while the over\/under is 236.5. Before making any Hornets vs. Cavaliers picks, check out the NBA predictions and betting advice from the SportsLine Projection Model<\/a>.<\/p>\n New users can also target the latest\u00a0Underdog promo code<\/a>, good for\u00a0$75 in bonus entries when you play $5 with the promo code CBSSPORTS2<\/a>\u00a0in select states.<\/p>\n The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in\u00a0betting<\/a>\u00a0profit for $100 players on its top-rated\u00a0NBA picks<\/a>\u00a0over the past eight-plus seasons. The model enters Week 14 of the 2025-26 NBA season on a sizzling 35-15 roll on top-rated NBA spread picks dating back to last season. Anyone following its\u00a0NBA betting<\/a>\u00a0advice at\u00a0sportsbooks<\/a>\u00a0and on\u00a0betting apps<\/a>\u00a0could have seen huge returns.<\/p>\n Now, the model has simulated Cavs vs. Hornets<\/a> 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model’s picks<\/a>. Here are several NBA odds<\/a> and NBA betting<\/a> lines for Hornets vs. Cavs:<\/p>\n Cavaliers vs. Hornets spread:\u00a0 \u00a0\u00a0<\/p>\n Cavaliers -2.5<\/p>\n Cavaliers vs. Hornets over\/under:\u00a0 \u00a0\u00a0<\/p>\n 236.5 points<\/p>\n Cavaliers vs. Hornets money line:\u00a0 \u00a0\u00a0<\/p>\n Cavaliers -143, Hornets +121<\/p>\n Cavaliers vs. Hornets picks:\u00a0 \u00a0\u00a0<\/p>\n See picks at SportsLine<\/a><\/p>\n Cavaliers vs. Hornets streaming:<\/p>\n Fubo<\/a>\u00a0(Try for free) \u00a0<\/p>\n New users can check out the latest\u00a0FanDuel promo code<\/a>\u00a0to\u00a0get $300 in bonus bets if your initial $5 wager wins<\/a>:<\/p>\n How to make Cavaliers vs. Hornets pick<\/p>\n After 10,000 simulations of Hornets vs. Cavaliers, SportsLine’s model is going Over on the total (222.5 points). Charlotte has seen four of its past five games go Over the total as the Hornets have been clicking on offense recently. Cleveland, meanwhile, has seen four of its last six games clear the total.\u00a0<\/p>\n The model is projecting that 10 players clear double figures with Donovan Mitchell and LaMelo Ball leading the scoring for their respective sides as the Over clears 63% of the time.\u00a0<\/p>\n The model also says one side of the spread hits well over 50% of the time. Head to SportsLine to see the model’s NBA picks<\/a>.\u00a0<\/p>\n