April 6, 2026, 12:35 a.m. ET<\/p>\n
The Cleveland Cavaliers<\/a> (49-29) and Memphis Grizzlies<\/a> (25-53) meet Monday at FedEx Forum in Memphis, Tennessee. Tip-off is scheduled for 8 p.m. ET. Let’s analyze NBA odds around the Cavaliers vs. Grizzlies odds and make our expert NBA picks and predictions<\/a> for the best bets.<\/p>\n Season series: Cavaliers lead 1-0<\/p>\n Cleveland won the first meeting 108-100 Nov. 15, although Memphis covered a 10.5-point underdog as the Under (241.5) easily cashed. The Cavs have won 6 consecutive meetings, but the Grizzlies are 3-1-1 against the spread (ATS) in the past 5 in the series, and the Under has a slight edge (3-2) in that span.<\/p>\n Cleveland has clinched a playoff spot, and it is on the verge of securing home-court advantage for the first round with 1 more victory in the final 4 games. It is also behind the New York Knicks by 1 game for the third spot in the Eastern Conference.<\/p>\n Cleveland won 117-108 Sunday against the Indiana Pacers, but it failed to cover as a 16.5-point favorite. G Donovan Mitchell went for 38 points, 6 rebounds and 6 assists with a pair of 3-pointers. The Cavs are 4-1 straight up (SU) in the past 5 games, but they’re 0-4 ATS in the past 4 outings, and 2-9 ATS in the previous 11 contests.<\/p>\n Memphis suffered a 131-115 loss Sunday at Milwaukee as a 7-point underdog as the Over (229.5) connected. F Rayan Rupert surprised with a triple-double (33 points, 10 rebounds, 10 assists), and he added 4 steals and a block with 2 3-pointers.<\/p>\n The Grizzlies have lost 4 in a row, and are just 2-17 SU in the past 19 games since March 3. It is 1-3 ATS in the past 4 games, and 3-6 ATS across the previous 9 contests. The Grizzlies have long since been eliminated from the Western Conference playoff picture.<\/p>\n Watch the NBA on Fubo!<\/a>Cavaliers at Grizzlies odds<\/p>\n Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub<\/a> for a full list. Lines last updated at 12:21 a.m. ET.<\/p>\n Moneyline (ML): Cavaliers -1200 (bet $1,200 to win $100) | Grizzlies +750 (bet $100 to win $750)Against the spread: Cavaliers -14 (-110) | Grizzlies +14 (-110)Over\/Under (O\/U): 238.5 (O: -110 | U: -110)Cavaliers at Grizzlies key injuries<\/p>\n Cavaliers<\/p>\n (Not yet submitted — below was for Sunday’s game)<\/p>\n C Jarrett Allen (knee) outG Sam Merrill (hamstring) outF Evan Mobley (calf) outG Jaylon Tyson (toe) outF Dean Wade (ankle) out<\/p>\n Grizzlies<\/p>\n (Not yet submitted — below was for Sunday’s game)<\/p>\n G Cedric Coward (back) outF GG Jackson (knee) outG Ty Jerome (ankle) outG Jahmai Mashack (concussion) outG Javon Small (thigh) outG Cam Spencer (back) out<\/p>\n For most recent updates: Official NBA injury report<\/a>.<\/p>\n Cavaliers at Grizzlies picks and predictionsPrediction<\/p>\n Cavaliers 123, Grizzlies 105<\/p>\n The Cavaliers (-1200) will set you back 12 times your potential return, and that’s way too much risk for not nearly enough reward, either with a singular bet or as part of a multi-leg parlay.<\/p>\n PASS and look to the spread instead.<\/p>\n The CAVALIERS -14 (-110) is worth a look laying the big points on the road. Cleveland is battling for seeding in the Eastern Conference, as it searches for home-court advantage in at least the first round. Memphis, on the other hand, is well out of the playoff picture, and it has an extensive injury list. With inexperienced players on no rest, it isn’t likely to end very well for the home side.<\/p>\n UNDER 238.5 (-110) might be the best play here. We have 2 teams playing on no rest, so the legs could be a bit heavy.<\/p>\n However, an Under play does come with risk, as the Over is 5-1 in the past 6 games for Memphis. It has allowed 117+ points in 19 consecutive outings, while allowing 124+ in 5 in a row.<\/p>\n The Cavaliers have allowed 113 or fewer points in 3 of the past 4 outings, and it has scored 122 or less in 4 in a row.<\/p>\n For more sports betting picks and tips, check out SportsbookWire.com<\/a> and BetFTW<\/a>.<\/p>\n Follow @danieledobish<\/a> on\u00a0Twitter\/X.\u00a0Follow SportsbookWire on Twitter\/X<\/a> and like us on Facebook<\/a>.<\/p>\n Access more NBA coverage:<\/p>\n HoopsHype<\/a> | Celtics Wire<\/a> | Nets Wire<\/a>\u00a0|\u00a0Rockets Wire<\/a>\u00a0|\u00a0Sixers Wire<\/a>\u00a0|\u00a0Thunder Wire<\/a>\u00a0|\u00a0Warriors Wire<\/a>\u00a0| LeBron Wire<\/a> |\u00a0Rookie Wire<\/a>\u00a0|\u00a0List Wire<\/a><\/p>\n