April 8, 2026, 10:46 a.m. ET<\/p>\n
The Portland Trail Blazers<\/a> (40-39) and San Antonio Spurs<\/a> (60-19) meet Wednesday at 9:30 p.m. ET from Frost Bank Center in San Antonio, Texas (ESPN). Let’s analyze NBA odds around the Trail Blazers vs. Spurs odds and make our expert NBA picks and predictions<\/a> for the best bets.<\/p>\n Season series: Tied 1-1<\/p>\n The Trail Blazers lost to the Denver Nuggets 137-132 in overtime Monday, snapping a 3-game winning streak. They covered as a 7.5-point road underdog with the Over (235.5) hitting. Portland has covered in 6 of its last 7 games and is 43-36 against the spread (ATS) on the season. It sits ninth in the Western Conference and is one game behind the eighth-place LA Clippers.<\/p>\n The Spurs are firmly in second place in the Western Conference, 3 games behind the top-seeded Oklahoma City Thunder and 9 games ahead of the third-place Denver Nuggets. San Antonio beat the Philadelphia 76ers 115-102 Monday, covering as an 8.5-point home favorite with the Under (236.5) hitting. The Spurs have won 12 of their last 13 games and covered in 7 of those. The Spurs are 43-34-2 ATS on the season.<\/p>\n Watch the NBA on Fubo!<\/a>Trail Blazers at Spurs odds<\/p>\n Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub<\/a> for a full list. Lines last updated at 10 a.m. ET.<\/p>\n Moneyline (ML): Trail Blazers +135 (bet $100 to win $135) | Spurs -165 (bet $165 to win $100)Against the spread (ATS): Trail Blazers +3.5 (-118) | Spurs -3.5 (-102)Over\/Under (O\/U): 229.5 (O: -110 | U: -110)Trail Blazers at Spurs key injuries<\/p>\n Trail Blazers<\/p>\n F Jerami Grant (calf) outG Shaedon Sharpe (fibula) doubtful<\/p>\n Spurs<\/p>\n G Stephon Castle (knee) doubtfulC Victor Wembanyama (rib) doubtful<\/p>\n For most recent updates: Official NBA injury report<\/a>.<\/p>\n Trail Blazers at Spurs picks and predictionsPrediction<\/p>\n Spurs 114, Trail Blazers 112<\/p>\n PASS.<\/p>\n Taking the Trail Blazers (+135) to win outright given the motivations behind this game is enticing. However, considering the spread and how well Portland has covered, that’s the preferred route.<\/p>\n BET TRAIL BLAZERS +3.5 (-118).<\/p>\n The Trail Blazers have been on a roll and have covered in 3 of their last 4 when closing as an underdog. Portland has won 8 of its last 11 contests, as well, so it has been playing at a high level.<\/p>\n The Spurs, likely short arguably their two best players in Castle and Wembanyama and basically locked into that second seed, don’t have much to play for. They have scored more than 118 points in just one of their last 3 games and are 1-3 ATS in their last 4 games when favored.<\/p>\n BET UNDER 229.5 (-110).<\/p>\n Assuming the players who are doubtful miss this one, there will be a lack of firepower, especially for San Antonio.<\/p>\n The Spurs are just 2-5 O\/U in their last 7 contests as well. Portland has allowed 106 points or fewer in 6 of its last 7 and has gone Under in 4 of those.<\/p>\n For more sports betting picks and tips, check out SportsbookWire.com<\/a> and BetFTW<\/a>.<\/p>\n Follow SportsbookWire on Twitter\/X<\/a> and like us on Facebook<\/a>.<\/p>\n Access more NBA coverage:<\/p>\n HoopsHype<\/a> | Celtics Wire<\/a> | Nets Wire<\/a>\u00a0|\u00a0Rockets Wire<\/a>\u00a0|\u00a0Sixers Wire<\/a>\u00a0|\u00a0Thunder Wire<\/a>\u00a0|\u00a0Warriors Wire<\/a>\u00a0| LeBron Wire<\/a> |\u00a0Rookie Wire<\/a>\u00a0|\u00a0List Wire<\/a><\/p>\n Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA TODAY Network may earn a commission. Prices were accurate at the time of publication but may change.<\/p>\n Gambling involves risk. 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