May 11, 2026, 10:28 p.m. ET<\/p>\n
The Minnesota Timberwolves<\/a> and San Antonio Spurs<\/a> meet Tuesday in Game 5 of their second-round Western Conference playoff series. Tip from Frost Bank Center in San Antonio, Texas, is set for 8 p.m. ET (NBC \/ Peacock). Let’s analyze NBA odds around the Timberwolves vs. Spurs odds and make our expert NBA picks and predictions<\/a> for the best bets.<\/p>\n Playoff series: Tied 2-2<\/p>\n The Timberwolves beat the Spurs 114-109 Sunday, covering as a 5.5-point home underdog with the Over (218.5) cashing. C Victor Wembanyama, the Spurs’ leading scorer and main defensive weapon, was ejected after playing just 12 minutes for a flagrant foul on F Naz Reid. Minnesota was led by G Anthony Edwards, who scored 16 of his game-high 36 points in the fourth quarter. He hit 13 of 22 shots.<\/p>\n San Antonio finished with 62 wins in the regular season, the second-best record in the NBA. It beat the Portland Trail Blazers in 5 games in the first round and has won Game 2 and Game 3 against the Timberwolves.<\/p>\n The Wolves downed the Denver Nuggets in 6 games in the first round, going 1-2 straight up and against the spread (ATS) on the road. They finished the regular season 48-33 straight up and 36-45 ATS.<\/p>\n Watch the NBA on Fubo!<\/a>Timberwolves at Spurs odds<\/p>\n Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub<\/a> for a full list. Lines last updated Monday at 10:17 p.m. ET.<\/p>\n Moneyline (ML): Timberwolves +320 (bet $100 to win $320) | Spurs -425 (bet $425 to win $100)Against the spread (ATS): Timberwolves +10.5 (-115) | Spurs -10.5 (-105)Over\/Under (O\/U): 218.5 (O: -110 | U: -110)Timberwolves at Spurs key injuries<\/p>\n Timberwolves<\/p>\n G Donte DiVincenzo (achilles) out<\/p>\n Spurs<\/p>\n G De’Aaron Fox (ankle) questionable<\/p>\n For most recent updates: Official NBA injury report<\/a>.<\/p>\n Timberwolves at Spurs picks and predictionsPrediction<\/p>\n Spurs 117, Timberwolves 104<\/p>\n PASS.<\/p>\n Avoid this play. The Spurs (-425) should win at home after the Wolves (+320) evened the series in Game 4, but San Antonio is far too expensive to consider here.<\/p>\n BET SPURS -10.5 (-105).<\/p>\n The Spurs have had the edge at home, while the Wolves have struggled on the road in the playoffs. San Antonio is 3-2 ATS in its 5 home games and has covered in each win. It has scored at least 114 points in 5 of its last 7 games, so the Spurs should put up enough to cover in this one.<\/p>\n The Timberwolves are 2-3 ATS on the road in the playoffs and have had offensive woes against an aggressive San Antonio defense. They have scored 108 points or fewer in all but 1 game in the series. Minnesota was just 15-17 ATS as an underdog during the regular season. It should struggle on the road after exceeding expectations in Game 4.<\/p>\n BET OVER 218.5 (-110).<\/p>\n With Wembanyama avoiding a suspension, he should be back and ready to dominate. The Spurs still put up 109 points without him for most of Game 4, so they have a deep arsenal of weapons. San Antonio has scored at least 115 points in 2 of its last 3 games, going Over in each of those.<\/p>\n The Timberwolves’ defense held the Nuggets to sub-100 points in 3 of 6 opening-round games, but they have had real issues with the Spurs. Minnesota has scored 111 points per game in the last 2 contests, while allowing at least 115 points per game.<\/p>\n Betting odds calculator<\/a><\/p>\n For more sports betting picks and tips, check out SportsbookWire.com<\/a> and BetFTW<\/a>.<\/p>\n Follow SportsbookWire on Twitter\/X<\/a> and like us on Facebook<\/a>.<\/p>\n Access more NBA coverage:<\/p>\n HoopsHype<\/a> | Celtics Wire<\/a> | Nets Wire<\/a>\u00a0|\u00a0Rockets Wire<\/a>\u00a0|\u00a0Sixers Wire<\/a>\u00a0|\u00a0Thunder Wire<\/a>\u00a0|\u00a0Warriors Wire<\/a>\u00a0| LeBron Wire<\/a> |\u00a0Rookie Wire<\/a>\u00a0|\u00a0List Wire<\/a><\/p>\n Our editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.<\/p>\n Gambling involves risk. 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