The Arizona Cardinals and New Orleans Saints play on Sunday, Sept. 7, at the Saints’ Caesars Superdome in a game on the NFL Week 1 schedule.
Which team will win the NFL Week 1 game?
Check out these NFL Week 1 picks and NFL Week 1 predictions for the game, which can be seen at 10 a.m. MST on CBS (stream with FUBO).
The Cardinals are a 6.5-point favorite over the Saints in NFL Week 1 odds for the game, courtesy of BetMGM Sportsbook.
Arizona is -275 on the moneyline, while New Orleans is +220. The over/under (point total) is set at 42.5 points.
NFL Week 1 picks: Cowboys vs Eagles | Chiefs vs Chargers | Buccaneers vs Falcons | Bengals vs Browns | Dolphins vs Colts | Panthers vs Jaguars | Raiders vs Patriots | Cardinals vs Saints | Steelers vs Jets | Giants vs Commanders | Titans vs Broncos | 49ers vs Seahawks | Lions vs Packers | Texans vs Rams | Ravens vs Bills | Vikings vs Bears | The Republic’s score predictions
Watch Cardinals at Saints live on FUBO (free trial)
Jeremy Cluff writes: “There’s been some talk about the Cardinals potentially being a sleeper playoff team in the NFC. Kyler Murray’s performance in Week 1 will add fuel to the fire of that conversation.”
Bookies.com: Bet the Cardinals to cover vs Saints
Bill Speros writes: “The Saints have a QB problem. The Cardinals don’t — for once. New HC Kellen Moore inherits a project in New Orleans. Arizona can start 4-2 with a win here. Take flight.”
The site’s formula predicts that the Cardinals will win the NFL Week 1 game against the Saints.
ESPN: Cardinals have a 57% chance to beat Saints
The site gives the Saints a 42.7% shot at winning the NFL Week 1 game, with the remaining percentage accounting for a tie.
Dimers: Cardinals 24, Saints 18
It writes: “After extensive simulations, our model gives the Cardinals a win probability of 72%, while the Saints have a win probability of 28%.”
Fansided: Cardinals 26, Saints 14
Lou Scataglia writes: “The New Orleans Saints might be the worst team in the NFL this year, so the Arizona Cardinals should win this one, period.”
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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