The Kansas City Chiefs (0-0) and Los Angeles Chargers (0-0) square off at Corinthians Arena in São Paulo, Brazil on September 5, 2025, starting at 8 p.m. ET, airing on YouTube. Kansas City is favored by 3 points in the matchup.
Chiefs vs. Chargers game infoGame day: Friday, September 5, 2025Game time: 8 p.m. ETTV channel: YouTubeLocation: São Paulo, BrazilStadium: Corinthians ArenaLive stream: Watch this game on Fubo (Regional restrictions may apply)
Watch Kansas City Chiefs vs. Los Angeles Chargers on Fubo! (Regional restrictions may apply)
Chiefs vs. Chargers odds & betting linesSpread favorite: Kansas City (-3)Moneyline: Kansas City (-171), Los Angeles (+143)Total: 45.5 points
NFL odds courtesy of BetMGM Sportsbook. Odds updated Tuesday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Chiefs vs. Chargers recent matchupsKansas City has the edge versus Los Angeles in the past five matchups between the two squads, putting together a 5-0 record.In those games versus the Chargers, the Chiefs have gone 3-2 against the spread, with those games going over the total on one occasion.Kansas City totaled 110 points in those five matchups, with Los Angeles putting up 83.Chiefs vs. Chargers 2024 betting insightsKansas City put together a 7-9-1 ATS record last year.Los Angeles went 12-4-1 ATS last season.Kansas City games last season featured more combined points than this contest’s total of 45.5 points eight times.Los Angeles played six games last season that finished with a point total above 45.5 points.Chiefs 2024 scoring insightsThe Chiefs put up 23.8 points per game at home last year, higher than their 21.7 average on the road.Defensively, Kansas City conceded fewer points at home (18.6 per game) than away (19.7).The Chiefs put up 16.3 points per game in the division last year, below their mark in non-division games of 26.1.The Chiefs conceded 19.3 points per game in the division, which was not quite as good as their average against the rest of the league of 19.1.Chargers 2024 scoring insightsThe Chargers scored 24.1 points per game at home last season, a little higher than their 23.2 average away from home.On defense, Los Angeles’ average at home, 22.0 points conceded, was worse than its average away, 13.9.The Chargers averaged fewer points in division games (23.3) than outside the division (23.8) last season, but not by much.The Chargers averaged more points conceded in division games (18.2) than against the rest of the league (17.5), but not by much.Chiefs injury reportChiefs:
Jared Wiley: Full Participation in Practice (Knee),
Drue Tranquill: Full Participation in Practice (Back),
Jawaan Taylor: Full Participation in Practice (Knee),
Kristian Fulton: Full Participation in Practice (Knee),
Jack Cochrane: Full Participation in Practice (Knee),
Marquise Brown: Full Participation in Practice (Ankle),
Omarr Norman-Lott: Limited Participation in Practice (Ankle),
Jalen Royals: Did Not Participate In Practice (Knee)Chargers injury reportChargers:
Elijah Molden: Limited Participation in Practice (Knee),
Najee Harris: Full Participation in Practice (Eye)
Watch Kansas City Chiefs vs. Los Angeles Chargers on Fubo! (Regional restrictions may apply)