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The schedule for the 2025 NFL season has been released. Here are a few games on our must-watch list.
Who will win the Indianapolis Colts vs the Miami Dolphins game?
The Miami Dolphins and Indianapolis Colts play on Sunday, Sept. 7, at the Colts’ Lucas Oil Stadium in a game on the NFL Week 1 schedule.
What do NFL Week 1 odds say about the game? Who are the NFL Week 1 predictions and NFL Week 1 picks taking in the game?
Which team has the best chance to win the game according to NFL Week 1 win probabilities?
Check out The Arizona Republic’s score prediction for the game, as well as Dolphins vs Colts picks, odds and win chances for the NFL Week 1 game, which can be seen at 10 a.m. MST on CBS (stream with FUBO).
NFL Week 1 picks: Cowboys vs Eagles | Chiefs vs Chargers | Buccaneers vs Falcons | Bengals vs Browns | Dolphins vs Colts | Panthers vs Jaguars | Raiders vs Patriots | Cardinals vs Saints | Steelers vs Jets | Giants vs Commanders | Titans vs Broncos | 49ers vs Seahawks | Lions vs Packers | Texans vs Rams | Ravens vs Bills | Vikings vs Bears | The Republic’s score predictions
Watch Dolphins at Colts on FUBO (free trial)
Miami Dolphins vs Indianapolis Colts prediction
The Arizona Republic is predicting a 31-20 win for the Dolphins over the Colts in the NFL Week 1 football game.
Jeremy Cluff writes: “How will Daniel Jones fare in his first start in Indianapolis? There may be some growing pains for Danny Dimes in the Colts’ offense. Tua Tagovailoa and the Dolphins will be able to outscore their opponent.”
Indianapolis Colts vs Miami Dolphins picks
Will the Dolphins or Colts win the game in NFL Week 1?
Bookies.com says to bet the Dolphins with the points against the Colts in the NFL Week 1 game.
Sports Betting Dime’s formula predicts a 5-point win for the Dolphins over the Colts.
Dimers.com predicts a final score of Colts 24, Dolphins 22.
Fansided’s prediction for the NFL Week 1 game is a 23-21 victory for the Dolphins against the Colts.
Miami Dolphins vs Indianapolis Colts win probabilities
The Colts have a 49.9% chance to beat the Dolphins, according to ESPN.
The site gives the Dolphins a 49.7% shot at winning the NFL Week 1 game, with the remaining percentage accounting for a tie.
Indianapolis Colts vs Miami Dolphins odds
The Colts are a 1.5-point favorite over the Dolphins in NFL Week 1 odds for the game, courtesy of BetMGM Sportsbook.
Indianapolis is -125 on the moneyline, while Miami is +105.
The over/under (point total) is set at 47 points.
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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