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The schedule for the 2025 NFL season has been released. Here are a few games on our must-watch list.
Who will win the Green Bay Packers vs Detroit Lions game?
The Detroit Lions and Green Bay Packers play on Sept. 7 at the Packers’ Lambeau Field in a game on the NFL Week 1 schedule.
What do NFL Week 1 odds say about the game? Who are NFL Week 1 predictions and NFL Week 1 picks taking in the game?
Which team has the best chance to win the game according to NFL Week 1 win probabilities?
Check out The Arizona Republic’s score prediction for the Sunday football game, as well as Lions vs Packers picks, odds and win chances for the NFL Week 1 game, which can be seen at 1:25 p.m. MST on CBS (stream with FUBO).
NFL Week 1 picks: Cowboys vs Eagles | Chiefs vs Chargers | Buccaneers vs Falcons | Bengals vs Browns | Dolphins vs Colts | Panthers vs Jaguars | Raiders vs Patriots | Cardinals vs Saints | Steelers vs Jets | Giants vs Commanders | Titans vs Broncos | 49ers vs Seahawks | Lions vs Packers | Texans vs Rams | Ravens vs Bills | Vikings vs Bears | The Republic’s score predictions
Watch Lions at Packers on FUBO (free trial)
Detroit Lions vs Green Bay Packers prediction
The Arizona Republic is predicting a 27-24 win for the Lions over the Packers in the NFL Week 1 Sunday football game.
Jeremy Cluff writes: “The Lions have won their last three games against the Packers at Lambeau Field. Jared Goff will make it four straight with a big win in Week 1.”
Green Bay Packers vs Detroit Lions picks
Will the Lions or Packers win the game in NFL Week 1?
Bookies.com says to bet the Lions on the moneyline in the game against the Packers.
Sports Betting Dime’s formula predicts a 2-point win for the Lions over the Packers.
Dimers.com predicts a final score of Packers 25, Lions 23.
Fansided’s prediction is a 28-24 win for the Packers against the Lions in NFL Week 1.
Detroit Lions vs Green Bay Packers win probabilities
The Lions have a 51.9% chance to beat the Packers, according to ESPN.
The site gives the Packers a 47.7% shot at winning the NFL Week 1 game, with the remaining percentage accounting for a tie.
Green Bay Packers vs Detroit Lions odds
The Packers are a 1.5-point favorite over the Lions in NFL Week 1 odds for the game, courtesy of BetMGM Sportsbook.
Green Bay is -125 on the moneyline, while Detroit is +105.
The over/under (point total) is set at 49.5 points.
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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