The Jacksonville Jaguars (0-0) are 3.5-point favorites heading into their matchup on Sunday, September 7, 2025 against the Carolina Panthers (0-0).
Jaguars vs. Panthers game infoGame day: Sunday, September 7, 2025Game time: 1 p.m. ETTV channel: FOXLocation: Jacksonville, FloridaStadium: EverBank StadiumLive stream: Watch this game on Fubo (Regional restrictions may apply)
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Jaguars vs. Panthers odds & betting linesSpread favorite: Jacksonville (-3.5)Moneyline: Jacksonville (-189), Carolina (+157)Total: 47 points
NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 2:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Jaguars vs. Panthers recent matchupsCarolina and Jacksonville have split their past two matchups (1-1).Jacksonville outscored Carolina 53-34 in those two head-to-head matchups.Jaguars vs. Panthers 2024 betting insightsJacksonville won 10 games against the spread last season, failing to cover seven times.Carolina won eight games against the spread last year, failing to cover nine times.In nine games last season, Jacksonville and its opponents scored more than 47 combined points.Carolina played 10 games last season that ended with a combined score higher than 47 points.Jaguars 2024 scoring insightsThe Jaguars averaged more points at home (22.6) than on the road (15.4) last year.On defense, Jacksonville allowed fewer points at home (22.3 per game) than on the road (28.6).The Jaguars averaged more points in division games (21.7) than outside the division (17.3) last year.The Jaguars conceded 21.0 points per game in divisional contests, which was lower than their 28.1 average versus the rest of the league.Panthers 2024 scoring insightsThe Panthers scored 21.1 points per game at home last season, better than their 18.9 average on the road.On defense, Carolina allowed fewer points at home (28.1 per game) than away (35.1).The Panthers scored 22.3 points per game in divisional matchups last year, which was better than their 18.8 average in non-division games.The Panthers averaged more points allowed in division games (36.5) than non-division games (28.6).Jaguars injury reportJaguars:
Cole Van Lanen: Limited Participation in Practice (Shoulder),
Wyatt Milum: Did Not Participate In Practice (Knee),
Montaric Brown: Did Not Participate In Practice (Ankle)Panthers injury reportPanthers:
Robert Hunt: Limited Participation in Practice (Foot),
Damarri Mathis: Limited Participation in Practice (Knee),
Damien Lewis: Limited Participation in Practice (Shoulder),
Ikem Ekwonu: Did Not Participate In Practice (Illness)
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