This week, the NFL travels to São Paulo, Brazil, where the Kansas City Chiefs (0-0) will play the Los Angeles Chargers (0-0) at Corinthians Arena on Friday, September 5, 2025. The Chiefs are favored by 3 points. The over/under for the contest is 46.5 points.

Last year, the Chiefs finished 15-2 and were knocked out of the playoffs in the Super Bowl round. Offensively, they averaged 22.6 points per game (15th in NFL), and they gave up 19.2 per game (fourth in NFL) defensively.

The Chargers scored 23.6 points per game (11th in league) and conceded 17.7 (first) last year, going 11-6 and getting knocked out of the playoffs in the Wild Card round.

Chiefs vs Chargers betting information

NFL odds courtesy of BetMGM Sportsbook. Odds updated Friday at 12:23 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread favorite: Kansas City (-3)Moneyline: Kansas City (-169), Los Angeles (+143)Total: 46.5 pointsChiefs 2024 betting insightsKansas City was 4-4-1 against the spread, and 7-2 overall, in away games last season.The Chiefs were 7-9-1 against the spread last year.Kansas City had two wins ATS (2-2-1) away from home as 3-point favorites or more.Against the spread, as 3-point favorites or more, the Chiefs went 5-7-1 last season.Kansas City went over the total in three of nine away games last season.The Chiefs had seven of their 17 games go over the point total last year.Chiefs players to watch (2024 stats)Patrick Mahomes: 3,928 PASS YDS / 245.5 YPG / 67.5% / 26 TD / 11 INT / 58 CAR / 307 RUSH YDS / 2 TDKareem Hunt: 200 CAR / 728 YDS / 56.0 YPG / 7 TD / 23 REC / 176 YDS / 13.5 YPG / 0 TDIsiah Pacheco: 83 CAR / 310 YDS / 44.3 YPG / 1 TD / 12 REC / 79 YDS / 11.3 YPG / 0 TDTravis Kelce: 97 REC / 823 YDS / 51.4 YPG / 3 TDXavier Worthy: 59 REC / 638 YDS / 39.9 YPG / 6 TDNoah Gray: 40 REC / 437 YDS / 27.3 YPG / 5 TDChiefs vs Chargers game infoDate: Friday, September 5, 2025Time: 8 p.m. ETCity: São Paulo, BrazilVenue: Corinthians ArenaTV channel: YouTubeLive stream: Watch on Fubo (Regional restrictions may apply)

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