The Minnesota Vikings will face take on their NFC North rival Chicago Bears in first edition of edition of Monday Night Football for the 2025 season. Kickoff is 8:15 p.m. ET.

Heading into Monday’s matchup, both the Bears and Vikings have several names on their final injury reports.

For Chicago, linebacker T.J. Edwards is now listed as doubtful with a hamstring injury, while defensive backs Josh Blackwell, Kyler Gordon, and Jaylon Johnson all carry a questionable tag. Running back Roschon Johnson is also questionable with a foot injury. On the other hand, wide receiver Devin Duvernay, running back Kyle Monangai, and defensive lineman Dominique Robinson practiced fully by the weekend and do not carry a game designation.

For Minnesota, running back Zavier Scott, defensive end Elijah Williams, and safety Harrison Smith have all been ruled out. Offensive tackle Christian Darrisaw is questionable with a knee injury. Wide receiver Jalen Nailor and linebacker Andrew Van Ginkel closed the week as full participants and are not listed with a game status.

These updates prompted Dimers’ analysts to reevaluate their Monday Night Football predictions and player stat projections using new simulations that factored in both teams’ latest roster developments.

The results of Dimers’ simulations were compared to updated sportsbook odds to compile the data-driven Vikings-Bears preview below.

Vikings vs. Bears betting preview

Explore the interactive widget below to view the current spread, over/under, and moneyline betting odds and probabilities for the Vikings-Bears game at Soldier Field.

Check out all the important details on Monday’s game, as well as the best odds sourced from the top sportsbooks in the country.

Game details

Key information on the Vikings vs. Bears matchup, including where the game is and what time it kicks off.

Teams: Minnesota Vikings vs. Chicago BearsDate: Monday, September 8, 2025Kickoff: 8:15 p.m. ETLocation: Soldier FieldNFL standings: Current NFL division standingsNFL injuries: Check the latest updates to the official NFL injury reportOdds

Odds for the key markets in the Vikings-Bears NFL matchup.

Spread: Vikings -1.5 (-105), Bears +1.5 (-110)Moneyline: Vikings -116, Bears +102Total: Over/Under 44 (-110/-110)

The odds and lines featured in this article are the best available from selected sports betting sites at the time of publication and are subject to change.

Fans of both teams can unlock betting bonuses with the NFL Week 1 betting promos from DraftKings, BetMGM, and FanDuel, while Bet365’s $300 sign-up offer has emerged as the most popular NFL betting deal among local fans in Illinois.

Expert prediction: Vikings vs. Bears

Using cutting-edge data analysis and advanced algorithms, the experts at Dimers have executed 10,000 simulations of Monday’s Vikings vs. Bears matchup.

According to Dimers’ popular predictive analytics model, the Vikings are more likely to defeat the Bears at Soldier Field. This prediction is based on the model giving the Vikings a 61% chance of winning the game.

Elsewhere on the betting board, Dimers predicts that the Vikings (-1.5) have a 60% chance of covering the spread, while the over/under total of 44 points has a 56% chance of staying under.

As always, these predictions and probabilities are accurate at the time of publication but are subject to change.

Vikings vs. Bears best bet

Our top pick for the Vikings vs. Bears Week 1 NFL game is to bet on the Vikings -1.5 (-105).

This betting advice is based on detailed modeling and valuable wagering intelligence, designed to deliver you the best possible plays.

Score prediction for Vikings vs. Bears

Dimers’ predicted final score for the Minnesota vs. Chicago game on Monday has the Vikings winning 22-19.

This expert prediction is based on each team’s average score following 10,000 game simulations, offering a glimpse into the potential outcome.

NFL boxscore projections props: Monday Night Football Week 1Minnesota VikingsFirst touchdown scorer predictionsJustin Jefferson: 9.1% probabilityJordan Mason: 8.6% probabilityAaron Jones: 8.6% probabilityAnytime touchdown predictionsJustin Jefferson: 38.1% probabilityJordan Mason: 36.4% probabilityAaron Jones: 36.4% probabilityProjected box score leadersQB passing yards: J.J. McCarthy, 224 yardsReceiving yards: Justin Jefferson, 82 yardsRushing yards: Aaron Jones, 53 yardsChicago BearsFirst touchdown scorer predictionsD’Andre Swift: 8.1% probabilityDJ Moore: 7.1% probabilityRome Odunze: 6.1% probabilityAnytime touchdown predictionsD’Andre Swift: 34.5% probabilityDJ Moore: 30.9% probabilityRome Odunze: 27.3% probabilityProjected box score leadersQB passing yards: Caleb Williams, 222 yardsReceiving yards: DJ Moore, 60 yardsRushing yards: D’Andre Swift, 56 yardsNFL Week 1: Vikings vs. Bears

Get ready for Monday’s game between the Vikings and Bears in Week 1 of the NFL season at Soldier Field, which is scheduled to start at 8:15 p.m. ET. We emphasize that all of the NFL best bets and NFL predictions in this article are based on 10,000 data-driven simulations of the Vikings vs. Bears matchup, and they are accurate at the time of publishing to help you make better decisions when placing bets at online sportsbooks.

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