Oddsmakers give the Los Angeles Rams (1-0) the advantage on Sunday, September 14, 2025 against the Tennessee Titans (0-1). Los Angeles is favored by 5.5 points.

Rams vs. Titans game infoGame day: Sunday, September 14, 2025Game time: 1 p.m. ETTV channel: CBSLocation: Nashville, TennesseeStadium: Nissan StadiumLive stream: Watch this game on Fubo (Regional restrictions may apply)Live stream: Watch this game on Paramount+ (Regional restrictions may apply)

Watch Los Angeles Rams vs. Tennessee Titans on Fubo! (Regional restrictions may apply)

Rams vs. Titans odds & betting linesSpread favorite: Los Angeles (-5.5)Moneyline: Los Angeles (-246), Tennessee (+201)Total: 41.5 points

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Rams vs. Titans recent matchupsThese two teams have played evenly over the last two matchups, with the series tied 1-1 over that span.Tennessee put up 51 points in those two matchups, while Los Angeles posted 43.Rams vs. Titans 2024 betting insightsLos Angeles put together a 9-8-0 record against the spread last season.Tennessee won just two games against the spread last year.Los Angeles and its opponents went over 41.5 combined points in 11 of 17 games last season.Tennessee’s games last season had a combined scoring total higher than 41.5 points in nine of 17 outings.Rams 2024 scoring insightsThe Rams scored 23.7 points per game at home last year, higher than their 19.3 average on the road.On defense, Los Angeles allowed more points at home (24.9 per game) than on the road (20.3).The Rams put up 18.8 points per game in divisional contests last season, which was less than their 23.1 average outside the division.The Rams given up 21.7 points per game in the division, which was lower than their mark against the rest of the league of 23.3.Los Angeles ranks 23rd in scoring offense over the last three contests (14 points per game), but it ranks third-best in scoring defense over that timeframe (9 points per game surrendered).Titans 2024 scoring insightsThe Titans averaged fewer points at home (16) than on the road (20.3) last season.On defense, Tennessee allowed fewer points at home (23 per game) than on the road (30.7).The Titans put up 18.7 points per game in the division last season, which was a little better than their average against the rest of the league of 18.1.The Titans given up 23 points per game in the division, which was better than their mark against the rest of the league of 29.3.Tennessee is fifth-worst in the league in points scored for the past three games (12 per game) and 14th in points allowed (20).Rams injury reportRams:
Davante Adams: Full Participation in Practice (NIR – Rest),
Esteban Avila: Did Not Participate In Practice (Ankle),
Colby Parkinson: Did Not Participate In Practice (Shoulder),
Kevin Dotson: Limited Participation in Practice (Ankle),
Rob Havenstein: Limited Participation in Practice (Ankle),
Davis Allen: Full Participation in Practice (Knee)Titans injury reportTitans:
JC Latham: Did Not Participate In Practice (Hip),
Arden Key: Limited Participation in Practice (Pectoral),
Quandre Diggs: Did Not Participate In Practice (Hand),
Kevin Winston Jr.: Limited Participation in Practice (Hamstring),
T’Vondre Sweat: Did Not Participate In Practice (Ankle),
L’Jarius Sneed: Limited Participation in Practice (Knee),
Kalel Mullings: Did Not Participate In Practice (Ankle)

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