The Jacksonville Jaguars (1-0) visit the Cincinnati Bengals (1-0) Sunday at Paycor Stadium in Cincinnati, Ohio. Kickoff is scheduled for 1 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Jaguars vs. Bengals odds and make our expert NFL picks and predictions for the best bets.

Jacksonville opened its season with a 26-10 win over the Carolina Panthers Sept. 7, covering as a 4½-point home favorite. QB Trevor Lawrence went 19-of-31 for 178 yards with a TD and an INT, and RB Travis Etienne Jr. carried 16 times for 143 yards.

Cincinnati escaped Week 1 with a 17-16 win at Cleveland after Browns PK Andre Szmyt missed a field goal and extra point in the second half. QB Joe Burrow went 14-of-23 for 113 yards and a TD, and RB Chase Brown carried 21 times for 43 yards and a score. The Bengals defense came up with 2 turnovers to secure the win.

The Bengals and Jaguars have not faced each other since Week 13 of 2023, when Cincinnati won 34-31 in OT on the road.

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Jaguars at Bengals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 1:48 p.m. ET.

Moneyline (ML): Jaguars +155 (bet $100 to win $155) | Bengals -190 (bet $190 to win $100)Against the spread (ATS): Jaguars +3.5 (-115) | Bengals -3.5 (-105)Over/Under (O/U): 49 (O: -110 | U: -110)

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Jaguars at Bengals key injuries

Jaguars

Bengals

Jaguars at Bengals picks and predictionsPrediction

Bengals 24, Jaguars 13

PASS.

There is better value on the Bengals’ (-190) spread.

BET BENGALS -3.5 (-105).

With the Bengals high-octane offense, it was their defense that came up big last week in their win. Expect the offense to find its groove this week against the Jaguars, creating opportunities and finding the end zone more easily.

The Jaguars benefited from playing a lousy Panthers team last week and will face more struggles against a new-look Bengals defense. While Etienne is expected to find similar success as last week, the team overall will not.

BET UNDER 49 (-110).

Despite the Bengals having what should be a top offense in the league and the Jaguars coming off a 26-point performance, this total is too high to bet the Over. Both teams easily hit the Under in Week 1.

The Bengals defense was +2 in the turnover battle last week, holding the Browns to just 16 points. The Jaguars also went +2 in turnovers, limiting the Panthers to 10 points.

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