The Tennessee Titans (0-1) will look to upset the Los Angeles Rams (1-0) on Sunday, September 14, 2025 at Nissan Stadium. The Rams are listed as favorites in this one, with the spread sitting at 5.5 points. The over/under is set at 41.5 in the outing.
In their most recent game, the Rams won against the Houston Texans, 14-9.
Rams quarterback Matthew Stafford went 21-for-29 for 245 yards, with one TD and no INTs, against the Texans.
The Titans lost to the Denver Broncos, 20-12, in their last game.
Rams vs Titans betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 12:35 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Los Angeles (-5.5)Moneyline: Los Angeles (-250), Tennessee (+203)Total: 41.5 pointsRams 2024 betting insightsAway from home last season, Los Angeles was 5-3 against the spread, and 5-3 overall.Against the spread, the Rams were 9-8-0 last year.The Rams had no wins ATS (0-2) as a 5.5-point favorite or more last season.Los Angeles hit the over in three of eight away games last year.Last year, eight of the Rams’ 17 games went over the point total.Rams players to watch (2024 stats)Stafford: 3,762 PASS YDS / 235.1 YPG / 65.8% / 20 TD / 8 INTKyren Williams: 316 CAR / 1,299 YDS / 81.2 YPG / 14 TD / 34 REC / 182 YDS / 11.4 YPG / 2 TDBlake Corum: 58 CAR / 207 YDS / 13.8 YPG / 0 TD / 7 REC / 58 YDS / 3.9 YPG / 0 TDDavante Adams: 85 REC / 1,063 YDS / 75.9 YPG / 8 TDPuka Nacua: 79 REC / 990 YDS / 90 YPG / 3 TDTutu Atwell: 42 REC / 562 YDS / 37.5 YPG / 0 TDRams vs Titans game infoDate: Sunday, September 14, 2025Time: 1 p.m. ETCity: Nashville, TennesseeVenue: Nissan StadiumTV channel: CBSLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Paramount+ (Regional restrictions may apply)
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