The second week of the 2025 campaign has arrived, and the Carolina Panthers are looking to put the first one way behind them.
Last Sunday saw the Panthers offer up a sloppy performance in their regular-season opener, taking a disappointing 26-10 defeat to the Jacksonville Jaguars as a result. But perhaps their latest road trip to the desert will go much more smoothly.
Can the offense operate efficiently?
Will the defense make a stand?
And can Carolina keep up their recent string of success against the Arizona Cardinals?
Here’s how you can tune in to today’s Week 2 matchup to find out . . .
Stream Panthers vs. Cardinals (free trial)
What channel is Panthers vs. Cardinals game on today?TV channel: CBSStreaming: NFL Sunday Ticket (YouTube) | Fubo (free trial)
Panthers vs. Cardinals will broadcast on CBS (in the orange areas of the map) in Week 2 of the 2025 season. Spero Dedes (play-by-play commentator), Adam Archuleta (color analyst) and Aditi Kinkhabwala (sideline reporter) are on the call.
Streaming options for the game include NFL Sunday Ticket on YouTube, CBS’ streaming service and Fubo, which offers a free trial to new subscribers.
Panthers vs. Cardinals time todayDate: Sunday, Sept. 14, 2025Time: 4:05 p.m. ET
Panthers vs. Cardinals will kick off on Sunday, Sept. 14 at 4:05 p.m. ET from State Farm Stadium in Glendale, Ariz.
Panthers vs. Cardinals predictions, picks, oddsPicks: Click here for expert predictions for Panthers vs. CardinalsSpread: Cardinals -7Over/under: 44.5Moneyline: Panthers +250, Cardinals -310
Odds courtesy of BetMGM as of Saturday, Sept. 14 (12:00 a.m. ET)
Panthers 2025 regular-season scheduleWeek 1: at Jacksonville Jaguars (Loss, 26-10)Week 2: at Arizona Cardinals (Sunday, Sept. 14 at 4:05 p.m. ET)Week 3: vs. Atlanta Falcons (Sunday, Sept. 21 at 1:00 p.m. ET)Week 4: at New England Patriots (Sunday, Sept. 28 at 1:00 p.m. ET)Week 5: vs. Miami Dolphins (Sunday, Oct. 5 at 1:00 p.m. ET)Week 6: vs. Dallas Cowboys (Sunday, Oct. 12 at 1:00 p.m. ET)Week 7: at New York Jets (Sunday, Oct. 19 at 1:00 p.m. ET)Week 8: vs. Buffalo Bills (Sunday, Oct. 26 at 1:00 p.m. ET)Week 9: at Green Bay Packers (Sunday, Nov. 2 at 1:00 p.m. ET)Week 10: vs. New Orleans Saints (Sunday, Nov. 9 at 1:00 p.m. ET)Week 11: at Atlanta Falcons (Sunday, Nov. 16 at 1:00 p.m. ET)Week 12: at San Francisco 49ers (Monday, Nov. 24, 8:15 p.m. ET)Week 13: vs. Los Angeles Rams (Sunday, Nov. 30 at 1:00 p.m. ET)Week 14: ByeWeek 15: at New Orleans Saints (Sunday, Dec. 14 at 4:25 p.m. ET)Week 16: vs. Tampa Bay Buccaneers (Sunday, Dec. 21 at 1:00 p.m. ET)Week 17: vs. Seattle Seahawks (TBD)Week 18: at Tampa Bay Buccaneers (TBD)
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