The Indianapolis Colts host the Denver Broncos on Sunday, Sept. 14, in NFL Week 2 action, and the Colts have been hit with concerning injuries in the defensive backfield.

Cornerback Jaylon Jones (hamstring) has been placed on injured reserve, and CB Charvarius Ward (concussion) and Laiatu Latu (hamstring) are out. Tight end Nate Adkins (ankle) and linebacker Dre Greenlaw (quad) are out for Denver.

Indianapolis Colts inactives today for Week 1 vs. Denver Broncos on Sept. 14

RB Tyler Goodson, DE Laiatu Latu, QB Riley Leonard (3rd quarterback), TE Will Mallory, T Luke Tenuta, CB Charvarius Ward

Denver Broncos inactives today for Week 1 vs. Indianapolis Colts on Sept. 14

QB Sam Ehlinger (3rd quarterback), RB Jaleel McLaughlin, LB Que Robinson, OT Frank Crum, DL Sai’Vion Jones, LB Dre Greenlaw, TE Nate Adkins

When is Indianapolis Colts vs Denver Broncos game in Week 2 of NFL season? Date, start time for Colts vs Broncos football game

4:05 p.m. ET Sunday, Sept. 14, 2025, at Lucas Oil Stadium in Indianapolis.

How to listen to Colts vs Broncos game on radio in Week 2? Streaming Broncos vs Colts at Lucas Oil StadiumRadio: 93.5, 97.1 and 107.5 FM in Indianapolis, with Matt Taylor (play-by-play), Rick Venturi (analysis) and Larra Overton (sideline reporting)Streaming: SiriusXM Channels 226, 381 (Broncos feed)

Joel A. Erickson covers the Colts all season. Get more coverage on IndyStarTV and with the Colts Insider newsletter.