The Atlanta Falcons (1-1) visit the Carolina Panthers (0-2) at Bank of America Stadium in Charlotte for a Week 3 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, September 21, including live updated odds and injury report news.

Panthers vs. Falcons live odds, moneyline, over/under

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Panthers vs. Falcons picks against the spread

Jordan Mendoza: Atlanta Falcons (-5)

Some may not realize it, but Atlanta’s defense has been insanely good in the first two weeks. The unit gives Bryce Young a long day at the office before pulling away at the end of the game.

Jon Hoefling: Carolina Panthers (+5)

Given how well these two teams know each other, it’s hard to assume a five-point victory for either side. It’s highly unlikely that Dave Canales will have Bryce Young throw the ball 55 times again, and a more balanced offensive approach should do wonders for their chances.

Tyler Dragon: Atlanta Falcons (-5)

Bryce Young’s had a bit of a regression through two weeks. The Falcons are coming off a nice win. Atlanta carries the momentum into Charlotte.

Christopher Bumbaca: Carolina Panthers (+5)

Holy line swing. I guess Bryce Young will do that. Speaking of him, let’s buy low on that stock and take the points here.

Blake Schuster: Carolina Panthers (+5)

This line flip has me worried. Especially after Atlanta didn’t look particularly great against the Minnesota Vikings in Week 2 (aside from Bijan Robinson). I’ll take the home team with the points and hope this one stays close.

Lorenzo Reyes: Atlanta Falcons (-5)

Carolina is averaging just 16 points per game and has slogged through the start of the season. The Falcons have the NFL’s second-best scoring defense (14.5). I love Atlanta in this spot.

Panthers vs. Falcons updated injury reportNFL Week 3 picks, predictions oddsUSA TODAY NFL picks against the spread standingsNameWeek 2 Record2025 RecordChris Bumbaca10-617-13-2Tyler Dragon11-516-14-2Jon Hoefling10-616-14-2Lorenzo Reyes9-716-14-2Blake Schuster9-716-14-2Jordan Mendoza9-715-15-2Super Bowl 60 updated odds