Heading into a game against the Tennessee Titans (0-2), the Indianapolis Colts (2-0) are monitoring 11 players on their injury report. The contest kicks off at 1 p.m. ET on Sunday, Sept. 21, at Nissan Stadium.
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Colts vs Titans TV channel & game infoGame day: Sunday, September 21, 2025Game time: 1 p.m. ETLocation: Nashville, TennesseeStadium: Nissan StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)
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Colts injury reportTyler Warren | TE (Questionable)Injury: ToePractice Status: Limited Participation in Practice2025 Receiving Stats: 16 Targets | 11 Receptions | 155 Yards | 0 TouchdownsCharvarius Ward | CB (Questionable)Injury: ConcussionPractice Status: Full Participation in Practice2025 Defensive Stats: 0.0 Sacks | 0.0 Tackles for Loss | 6 Tackles | 0 Interceptions | 0 Passes DefendedSamson Ebukam | DEInjury: RestPractice Status: Did Not Participate In PracticeDeForest Buckner | DTInjury: RestPractice Status: Did Not Participate In Practice2025 Defensive Stats: 0.0 Sacks | 2.0 Tackles for Loss | 9 Tackles | 0 Interceptions | 0 Passes DefendedGrover Stewart | DTInjury: NIR – RestPractice Status: Full Participation in Practice2025 Defensive Stats: 0.0 Sacks | 1.0 Tackles for Loss | 8 Tackles | 0 Interceptions | 0 Passes DefendedBernhard Raimann | OTInjury: IllnessPractice Status: Full Participation in Practice2025 Season Stats: 2 Games PlayedLaiatu Latu | DEInjury: HamstringPractice Status: Full Participation in PracticeTyler Goodson | RBInjury: ElbowPractice Status: Full Participation in Practice2024 Rushing: 32 Attempts | 153 Yards | 1 TouchdownJosh Downs | WRInjury: AnklePractice Status: Full Participation in Practice2025 Receiving Stats: 11 Targets | 8 Receptions | 63 Yards | 0 TouchdownsAustin Ajiake | LBInjury: ThroatPractice Status: Full Participation in Practice2025 Season Stats: 1 Games PlayedJoe Bachie | LBInjury: QuadricepPractice Status: Full Participation in Practice2025 Defensive Stats: 0.0 Sacks | 0.0 Tackles for Loss | 9 Tackles | 0 Interceptions | 0 Passes DefendedColts insightsThe Colts score 31 points per game, 4.5 more than the Titans allow per outing (26.5).When Indianapolis puts up more than 26.5 points, it is 2-0 against the spread and 2-0 overall.Indianapolis averages 67.5 more yards per game (445.5) than Tennessee allows per contest (378).Colts vs Titans odds
NFL odds courtesy of BetMGM. Odds updated Saturday at 1:14 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: Colts (-4.5)Moneyline: Colts (-207), Titans (+170)Total: 43.5 points
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