Division rivals Los Angeles (2-0) and Denver (1-1) will meet in a matchup of AFC West teams on Sunday, September 21, 2025 at SoFi Stadium. The Chargers are listed as favorites in this one, with the spread sitting at 3 points. The over/under is 45.5 in the outing.
Last time out, the Chargers defeated the Las Vegas Raiders, with 20-9 being the final score.
The Bolts’ Justin Herbert went 19-for-27 for 242 yards versus the Raiders, with two TDs and no INTs.
The Broncos‘ last game was versus the Indianapolis Colts, and they lost by a score of 29-28.
Chargers vs Broncos betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 2:07 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Los Angeles (-3)Moneyline: Los Angeles (-154), Denver (+130)Total: 45.5 pointsChargers betting insightsAt home last season, Los Angeles was 5-2-1 against the spread and 5-3 overall.The Chargers have covered the spread two times this season (2-0-0).Los Angeles was 3-1 ATS as 3-point favorites or more at home last season.The Chargers are a perfect 1-0 ATS when playing as at least 3-point favorites.Last year, in eight home games, Los Angeles went over the total five times.Chargers games have gone over the total once this season.Chargers leadersHerbert: 560 PASS YDS / 280 YPG / 72.1% / 5 TD / 0 INT / 16 CAR / 63 RUSH YDS / 0 TDOmarion Hampton: 23 CAR / 72 YDS / 36 YPG / 0 TD / 3 REC / 14 YDS / 7 YPG / 0 TDQuentin Johnston: 8 REC / 150 YDS / 75 YPG / 3 TDKeenan Allen: 12 REC / 129 YDS / 64.5 YPG / 2 TDLadd McConkey: 11 REC / 122 YDS / 61 YPG / 0 TDChargers vs Broncos game infoDate: Sunday, September 21, 2025Time: 4:05 p.m. ETCity: Inglewood, CaliforniaVenue: SoFi StadiumTV channel: CBSLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Paramount+ (Regional restrictions may apply)
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