Sportsbooks give the Baltimore Ravens (1-1) the advantage on Monday, September 22, 2025 against the Detroit Lions (1-1). Baltimore is favored by 4.5 points. The point total has been set at 53.5.

Find insights on prop bet options to include in a parlay below in this article, including first to score and prop bets for the top players.

Ravens vs. Lions game odds

NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 1:41 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread: Ravens -4.5 (-110 to cover)Moneylines: Ravens -235, Lions +195Total: 53.5 points (Over: -110, Under: -110)Pick ATS: Lions (+4.5)Pick OU: Under (53.5)Prediction:
Ravens 27 – Lions 26First TD odds and insights

First TD odds: Ravens -165, Lions +125

The Ravens have scored the opening touchdown in one game out of the two they’ve played thus far.Each of Baltimore’s one first touchdown was a passing score.In the first quarter, the Ravens have not scored a touchdown this season.The Lions have scored the first TD one time this season out of two games played.Each of the one first touchdown scored by Detroit was via a run.Looking at just first quarters, the Lions have scored two touchdowns, the second-most of all teams this year.

Watch Baltimore Ravens vs. Detroit Lions on Fubo!

Lamar Jackson player propsPassing yard prop: Over/under 234.5 yardsRushing yard prop: Over/under 45.5 yardsLamar Jackson averages 217.0 passing yards per game this season, which is less than his prop bet total for this matchup of 234.5.Jackson has yet to go over on his passing yards prop bet this season in two chances.Jackson has a passing touchdown in all two games this season, and multiple passing TDs each time.Derrick Henry player propsRushing yard prop: Over/under 84.5 yardsReceiving yard prop: Over/under 4.5 yardsMonday’s rushing yards prop bet for Derrick Henry is set at 84.5. That is 11.5 fewer yards than his season average of 96.0.Henry has hit the over on his rushing yards total one time in two opportunities this season.Henry scored multiple touchdowns on the ground once this year, but that was his only game with at least one rushing score.Jared Goff player propsPassing yard prop: Over/under 263.5 yardsJared Goff has racked up 279.5 passing yards per game this season, 16.0 yards more than Monday’s over/under.Goff has gone over his passing yard total once this season (50.0% of total opportunities).Goff has a passing touchdown in all two games this year, with multiple passing TDs in one of them.Amon-Ra St. Brown player propsReceiving yard prop: Over/under 72.5 yardsAmon-Ra St. Brown’s 80.0 receiving yards per game are 7.5 more than his prop bet over/under for Monday’s game (72.5).St. Brown has gone over on his prop bets for receiving yards in one of two games this year (50.0%).In one of two games this year, St. Brown has a receiving touchdown (and he scored multiple receiving TDs in that game).