The San Francisco 49ers have finalized their inactive list ahead of Sunday’s Week 3 home opener against the Arizona Cardinals. With rosters limited to 48 active players on gameday, six players will be sidelined for the NFC West matchup at Levi’s® Stadium.

The team officially downgraded quarterback Brock Purdy (shoulder/toe) and wide receiver Jauan Jennings (ankle/shoulder) from questionable to OUT on Sunday morning. With Purdy unavailable, Mac Jones will take his second start under center for the 49ers.

Here are the 49ers inactives for Week 3 against the Cardinals: