Through four games, the Oregon Ducks had yet to match up with anyone close to their skill level. And the results showed it, as they won by an average of 41.5 points. While, for the most part, they were excellent in each game, there wasn’t a ton to be taken away until Week 5.
That was when they were scheduled to travel to Penn State to take on the Nittany Lions, a top five team in the AP Poll. The fact that Penn State, with a stadium capacity of over 100,000-plus, had scheduled their yearly “whiteout” game against Oregon only raised the anticipation level. Nearly every question that anyone had about the Ducks‘ dominant start would be answered on Saturday evening.
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That was the feeling before the game, and it was proved true. Both the Ducks and Nittany Lions had their moments, coming back from the opposing team making a crucial run to go on a run of their own. But in the end, Oregon prevailed in double overtime with a 30-24 victory, proving to the nation that they’re legit national title contenders.
Where does that leave them in the national title odds after Week 5? Let’s check it out.
Ohio State Buckeyes (+500)
Ohio State Buckeyes wide receiver Jeremiah Smith (4) celebrates an 87-yard touchdown catch during the first half of the NCAA football game against Grambling State at Ohio Stadium on Sept. 6, 2025.
Previous Odds: +600
Week 5 Result: W 24-6 vs. Washington
Record: 4-0, 1-0 Big Ten
Oregon Ducks (+600)
Oregon quarterback Dante Moore throws a pass as the Oregon Ducks face the Penn State Nittany Lions on Sept. 27, 2025, at Beaver Stadium in University Park, Pennsylvania.
Previous Odds: +700
Week 5 Result: W 30-24 vs. Penn State
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Record: 5-0, 2-0 Big Ten

Texas quarterback Arch Manning (16) is tackled by San Jose State after keeping the ball for yardage during the first half at Darrell K Royal-Texas Memorial Stadium.
Previous Odds: +750
Week 5 Result: Bye
Record: 3-1
Alabama Crimson Tide (+800)
Sep 27, 2025; Athens, Georgia, USA; Alabama Crimson Tide offensive lineman Kadyn Proctor (74) celebrates with quarterback Ty Simpson (15) after defeating the Georgia Bulldogs at Sanford Stadium. Mandatory Credit: Brett Davis-Imagn Images
Previous Odds: +1200
Week 5 Result: W 24-21 vs. Georgia
Record: 3-1, 1-0 SEC
Penn State Nittany Lions (+800)
Sep 27, 2025; University Park, Pennsylvania, USA; Penn State Nittany Lions head coach James Franklin and quarterback Drew Allar (15) react after losing to the Oregon Ducks at Beaver Stadium. Mandatory Credit: James Lang-Imagn Images
Previous Odds: +650
Week 5 Result: L 30-24 vs. Oregon
Record: 3-1, 0-1 Big Ten
Georgia Bulldogs (+950)
Georgia quarterback Gunner Stockton (14) runs the ball past Marshall defensive back Josh Pierre-Louis (11) during the first half of a NCAA college football game against Marshall in Athens, Ga., on Saturday, August. 30, 2025.
Previous Odds: +700
Week 5 Result: L 24-21 vs. Alabama
Record: 3-1, 1-1 SEC
Miami Hurricanes (+1400)
Sep 20, 2025; Miami Gardens, Florida, USA; Miami Hurricanes running back CharMar Brown (6) carries the football against the Florida Gators during the fourth quarter at Hard Rock Stadium. Mandatory Credit: Sam Navarro-Imagn Images
Previous Odds: +1500
Week 5 Result: Bye
Record: 4-0
Oklahoma Sooners (+1900)
Sep 13, 2025; Philadelphia, Pennsylvania, USA; Oklahoma Sooners quarterback John Mateer (10) rushes against Temple Owls linebacker Ty Davis (10) in the first half at Lincoln Financial Field. Mandatory Credit: Kyle Ross-Imagn Images
Previous Odds: +1800
Week 5 Result: Bye
Record: 4-0, 1-0 SEC

Ole Miss linebacker TJ Dottery (6) celebrates during a college football game between Ole Miss and LSU at Vaught-Hemingway Stadium in Oxford, Miss., on Saturday, Sept. 27, 2025. Ole Miss defeated LSU 24-19.
Previous Odds: +3000
Week 5 Result: W 24-19 vs. LSU
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Record: 5-0, 3-0 SEC
Texas A&M Aggies (+2200)
Sep 13, 2025; South Bend, Indiana, USA; Texas A&M Aggies quarterback Marcel Reed (10) looks to make a pass during the first half against the Notre Dame Fighting Irish at Notre Dame Stadium. Mandatory Credit: Michael Caterina-Imagn Images
Previous Odds: +2200
Week 5 Result: W 16-10 vs. Auburn
Record: 4-0, 1-0 SEC
LSU Tigers (+3000)
LSU wide receiver Chris Hilton Jr. (3) catches the ball during a college football game between Ole Miss and LSU at Vaught-Hemingway Stadium in Oxford, Miss., on Saturday, Sept. 27, 2025. Ole Miss defeated LSU 24-19.
Previous Odds: +1400
Week 5 Result: L 24-19 vs. Ole Miss
Record: 4-1, 1-1 SEC
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This article originally appeared on Ducks Wire: Where Oregon Ducks land in national title odds after Week 5 victory