Los Angeles Rams quarterback Matthew Stafford has a difficult matchup in Week 5 (Thursday at 8:15 p.m. ET), up against the San Francisco 49ers. The 49ers are giving up the sixth-fewest passing yards in the NFL, 165 per game.
Stafford has piled up 1,114 yards passing (278.5 per game) with eight TDs and two picks this season. Stafford has added -4 rushing yards on 10 carries while averaging -1.0 yards per contest.
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Stafford vs. the 49ers
Stafford vs the 49ers (since 2021): 6 GP / 257.7 PASS YPG / 10 PASS TD
Not a single opposing quarterback has registered 300 or more passing yards in an outing against San Francisco this season.
The 49ers have allowed one or more passing TDs to three opposing quarterbacks this season.
One opposing quarterback have thrown for two or more TDs in a game against San Francisco in 2025.
The 49ers have allowed three or more TD passes in an outing to one opposing QB this season.
The 49ers surrender 165 passing yards per game, the NFL’s sixth-ranked pass defense this season.
The 49ers’ defense is ranked seventh in the NFL with five passing TDs conceded so far this year.
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Stafford Passing Insights
Stafford has topped his passing yards prop total in three of four opportunities this season.
The Rams, who are 13th in NFL play in points scored, have passed 56.1% of the time while running 43.9%.
With 136 attempts for 1,114 passing yards, Stafford is fifth in league action with 8.2 yards per attempt.
Stafford has thrown for a touchdown in all four games this season, with more than one TD pass three times.
He has eight total touchdowns this season (72.7% of his team’s 11 offensive TDs).
Stafford has attempted 20 passes in the red zone (51.3% of his team’s red zone plays).
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Stafford’s Recent Performance