Josh Allen and the Buffalo Bills (4-0) will host Drake Maye and the New England Patriots (2-2) on Sunday at 8:20 p.m. ET, in a matchup between a pair of excellent QBs.
The Bills faced the New Orleans Saints in their most recent game, winning 31-19. The Patriots’ last outing finished in a 42-13 win over the Carolina Panthers. Allen threw for 209 yards, with two touchdowns and one interception on 16-of-22 passing (72.7%) for the Bills in that matchup against the Saints. He also added seven carries for 45 yards and one rushing touchdown. James Cook took 22 carries for 117 yards (5.3 yards per carry) and one touchdown, while adding three receptions for 18 yards in the passing game. Khalil Shakir led the receiving charge against the Saints, catching five passes for 69 yards and one touchdown. Maye threw for 203 yards for the Pats against the Panthers, going 14-for-17 (82.4%) with two touchdowns and no interceptions. He added three carries for 11 yards and one touchdown. Rhamondre Stevenson put together a nine-carry, 38-yard game (4.2 yards per attempt), while tacking on one reception for three yards. Stefon Diggs collected six catches for 101 yards (on seven targets).
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Bills vs. Patriots game infoGame day: Sunday, October 5, 2025Game time: 8:20 p.m. ETLocation: Orchard Park, New YorkStadium: Highmark StadiumTV channel: NBC UniversoLive stream: Fubo (Watch Now!)Live stream: Peacock (Watch Now!)
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Bills vs. Patriots betting info
NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 11:05 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Bills (-8)Moneyline: Bills (-450), Patriots (+340)Total: 49.5 points
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