The Kansas City Chiefs (2-2) are less than a touchdown favorite (-3.5) on Monday, October 6, 2025 against the Jacksonville Jaguars (3-1).
Chiefs vs. Jaguars game infoGame day: Monday, October 6, 2025Game time: 8:15 p.m. ETTV channel: ABC/ESPNLocation: Jacksonville, FloridaStadium: EverBank StadiumLive stream: Watch this game on Fubo (Regional restrictions may apply)
Watch Kansas City Chiefs vs. Jacksonville Jaguars on Fubo! (Regional restrictions may apply)
Chiefs vs. Jaguars odds & betting linesSpread favorite: Kansas City (-3.5)Moneyline: Kansas City (-185), Jacksonville (+154)Total: 45.5 points
NFL odds courtesy of BetMGM Sportsbook. Odds updated Friday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Chiefs vs. Jaguars recent matchupsKansas City holds the edge versus Jacksonville over the last five matchups between the two squads, recording a 5-0 record.Kansas City outscored Jacksonville 141-86 in those five head-to-head matchups.Chiefs vs. Jaguars betting insightsKansas City has won two games against the spread so far this season (2-2-0). The Chiefs split the two games they have played as the moneyline favorite this season. Jacksonville has three wins against the spread in four opportunities this season (3-1-0). The Jaguars have played as an underdog on the moneyline two times so far this season, and they split the two games.Chiefs scoring insightsThe Chiefs’ defense has been wreaking havoc on opposing offenses over the last three games, ranking second-best by surrendering only 16.3 points per game. On the offensive side of the ball, they rank 12th in the NFL over that three-game stretch (25.3 points per game).Jaguars scoring insightsOn offense in their previous three games, the Jaguars are averaging 23.3 points, 18th in the league. On defense, they are giving up 20.7, which puts them 11th.Chiefs injury reportChiefs:
Xavier Worthy: Full Participation in Practice (Shoulder),
James Winchester: Full Participation in Practice (Hamstring),
Jawaan Taylor: Full Participation in Practice (Knee),
JuJu Smith-Schuster: Full Participation in Practice (Knee),
Charles Omenihu: Full Participation in Practice (Ankle),
Patrick Mahomes: Full Participation in Practice (Groin),
Michael Danna: Full Participation in Practice (Quad),
Marquise Brown: Full Participation in Practice (Ankle),
Kristian Fulton: Limited Participation in Practice (Ankle)Jaguars injury reportJaguars:
Bhayshul Tuten: Limited Participation in Practice (Shoulder),
Chuma Edoga: Limited Participation in Practice (Knee),
Eric Murray: Limited Participation in Practice (Neck),
Ezra Cleveland: Limited Participation in Practice (Concussion),
Wyatt Milum: Limited Participation in Practice (Knee),
Dyami Brown: Limited Participation in Practice (Shoulder),
Patrick Mekari: Limited Participation in Practice (Knee),
Travon Walker: Did Not Participate In Practice (Wrist),
Anton Harrison: Limited Participation in Practice (Elbow),
Yasir Abdullah: Did Not Participate In Practice (Hamstring)
Watch Kansas City Chiefs vs. Jacksonville Jaguars on Fubo! (Regional restrictions may apply)