At EverBank Stadium on Monday, Patrick Mahomes and the Kansas City Chiefs (2-2) play Travis Etienne and the Jacksonville Jaguars (3-1) in a matchup featuring two outstanding runners, beginning at 8:15 p.m. ET.
In their most recent outing, the Chiefs won 37-20 over the Baltimore Ravens. The Jaguars’ last game ended in a 26-21 win over the San Francisco 49ers. Mahomes had 270 yards on 25-of-37 passing (67.6%) for the Chiefs in that matchup against the Ravens, with four touchdowns and no interceptions. Xavier Worthy totaled 38 rushing yards on two carries (19.0 yards per carry). He also had five catches for 83 yards. Travis Kelce led the receiving charge against the Ravens, catching five passes for 48 yards. Trevor Lawrence went 21-for-31 with 174 yards, one touchdown and no interceptions for the Jags against the 49ers. In that matchup, Etienne had a 19-carry, 124-yard game (6.5 yards per attempt) with one touchdown. He also added one reception for one yard. Brian Thomas collected five catches for 49 yards (on seven targets).
Below we dive into all of the details you need before this matchup begins, including how to watch on Fubo.
Watch Kansas City Chiefs vs. Jacksonville Jaguars on Fubo! (Regional restrictions may apply)
Chiefs vs. Jaguars game infoGame day: Monday, October 6, 2025Game time: 8:15 p.m. ETLocation: Jacksonville, FloridaStadium: EverBank StadiumTV channel: ESPN DeportesLive stream: Fubo (Watch Now!)
Watch Kansas City Chiefs vs. Jacksonville Jaguars on Fubo! (Regional restrictions may apply)
Chiefs vs. Jaguars betting info
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 3:05 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Chiefs (-3.5)Moneyline: Chiefs (-185), Jaguars (+150)Total: 45.5 points
Watch Kansas City Chiefs vs. Jacksonville Jaguars on Fubo! (Regional restrictions may apply)