Brock Purdy won’t be taking the field on Thursday night after all.

The San Francisco 49ers ruled Purdy out for Thursday’s matchup with the Los Angeles Rams officially on Wednesday afternoon due to a toe injury. That paves the way for backup Mac Jones, who has won a pair of games already this season filling in for Purdy, to get the start at SoFi Stadium.

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Purdy went down with a toe injury in the Niners’ season-opener, and missed a pair of games recovering. He returned for Sunday’s loss to the Jacksonville Jaguars, and threw for 309 yards with two touchdowns and two interceptions. He said after the game that his toe wasn’t much of an issue, but soreness started bothering him later that night.

He has not practiced with the team normally all week, but was hopeful that he could return even with it being a short week.

“If I can play this game, I want to play,” Purdy said on Tuesday, via ESPN. “Obviously, I want to get right and get healthy and everything, but we need to win this game against the Rams. So that’s how I’m looking at it.”

Further specifics on the severity of Purdy’s toe injury are not yet known. According to The Athletic’s Matt Barrows, the 49ers are leery of it becoming a recurring injury this season — which tracks, especially if they aren’t pushing Purdy to play during a short week and taking extra time to recover. He also apparently isn’t healthy enough to be their emergency backup, either.

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Thankfully for San Francisco, Jones has been very solid this season. He’s thrown for 563 yards and four touchdowns with one interception in two starts this season while, most importantly, picking up a pair of wins. The former No. 15 overall draft pick was briefly limited with a knee injury, but he’s since been cleared to return.

Jones, however, will have limited options to help him offensively. Wide receivers Jauan Jennings, Ricky Pearsall and Jordan Watkins were all ruled out due to various injuries Wednesday. The team is also still without wide receiver Brandon Aiyuk, who is recovering from a knee injury, and tight end George Kittle, who is out with a hamstring injury.

The Rams also enter Thursday’s contest with a 3-1 record, fresh off a 27-20 win over the Indianapolis Colts last weekend. Quarterback Matthew Stafford completed 29 of 41 for 375 passing yards with three touchdowns in that win, while Puka Nacua had 170 yards and a score on 13 catches.