The Arizona Cardinals (2-2) will host the Tennessee Titans (0-4) on Sunday at 4:05 p.m. ET.

The Cardinals rank 23rd in scoring offense (20.5 points per game) and sixth in scoring defense (18.5 points allowed per game) this season. The Titans’ offense has been bottom-five in total offense this season, putting up 210.5 total yards per game, which ranks second-worst in the NFL. On defense, they rank 25th with 368.5 total yards allowed per contest.

Watch Arizona Cardinals vs. Tennessee Titans on Fubo! (Regional restrictions may apply)

Cardinals vs Titans: live streaming info, TV channel & game timeGame day: Sunday, October 5, 2025Game time: 4:05 p.m. ETLocation: Glendale, ArizonaStadium: State Farm StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)

Watch Arizona Cardinals vs. Tennessee Titans on Fubo! (Regional restrictions may apply)

Cardinals vs Titans betting lines

NFL odds courtesy of BetMGM. Odds updated Sunday at 4:21 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread Favorite: Cardinals (-7.5)Moneyline: Cardinals (-433), Titans (+333)Total: 41.5 points

Watch Arizona Cardinals vs. Tennessee Titans on Fubo! (Regional restrictions may apply)