The New England Patriots are set to take on the Buffalo Bills in one of the most anticipated games on the schedule at Orchard Park on Sunday night.

The Patriots are coming off a resounding 42-13 win over the Carolina Panthers last week. They had everything going their way in the game, including an 87-yard punt returned for a touchdown by cornerback Marcus Jones. Quarterback Drake Maye was extremely efficient on the day, going 14-of-17 passing for 203 yards and two touchdowns. He also rushed for a touchdown on the ground.

Advertisement

Can he keep up the momentum on the road against the Bills? All eyes will be on the second-year quarterback when going head-to-head with a banged-up Bills defense that has been exploitable this season.

Maye will need to get production out of his receivers, starting with four-time Pro Bowl wideout Stefon Diggs, who will make his long-awaited return to Buffalo on Sunday. He posted his first 100-plus yard game as a member of the Patriots last week.

Meanwhile, the Bills struggled with the New Orleans Saints, but they still found a way to come out with a 31-19 victory. Quarterback Josh Allen finished the game going 15-of-22 passing for 209 yards, two touchdowns and an interception.

However, running back James Cook was the key factor in the game with 22 carries for 117 yards and a touchdown. That game marked Cook’s third 100-yard rushing game this season.

Advertisement

The Patriots and Bills have a storied history, but the competition between the two teams could heat up even more with Maye in the fold. New England now has a franchise quarterback to go toe-to-toe with Allen.

A win on Sunday for the Patriots would be a statement victory for the team. Here are the official picks from the Patriots Wire staff:

Danny Jaillet prediction: Patriots 28, Bills 24

Jordy McElroy prediction: Patriots 30, Bills 33

Sophie Weller prediction: Patriots 24, Bills 27

Follow Patriots Wire on Twitter and Facebook.

This article originally appeared on Patriots Wire: Patriots Wire staff predictions for Patriots-Bills Week 5 game