New York Giants open as heavy home underdogs vs. Eagles in Week 6

The New York Giants (1-4) host the reigning Super Bowl champions, the Philadelphia Eagles (4-1), at MetLife Stadium this Thursday Night Football.

The point spread has opened at Eagles -7 with the over/under currently sitting at 41.5 total points, per BetMGM. The moneyline as of Monday morning is a prohibitive Eagles -400, Giants +110.

This is the 183rd meeting (including playoffs) between the two franchises, going back to the early days of the NFL (1933). Philadelphia leads the series, 93-87-2 and has won seven of the last eight meetings.

The Giants lost to the previously winless Saints, 26-14, in New Orleans on Sunday. The Eagles lost their first game of the season on Sunday, 21-17, to the Denver Broncos at home.

The Giants were swept by the Eagles in 2024, losing 28-3 at home in Week 7 and 20-13 on the road in Week 18.

The Eagles are 3-2 against the spread. The Giants are 2-3. Four of the Giants’ five games this far have gone under. The over in Eagles’ games is 2-3.