Here are some key trends and stats to parse before placing any bets on James Cook’s player prop bets for Monday’s game, which starts at 7:15 p.m. ET on ESPN. Cook and the Buffalo Bills (4-1) meet the Atlanta Falcons (2-2) in Week 6 at Mercedes-Benz Stadium in Atlanta, Georgia.
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James Cook week 6 player propsMatchup: Buffalo Bills at Atlanta FalconsTime: 7:15 p.m. ETDate: October 13, 2025Rushing yards prop: Over 70.5 (-115)Receiving yards prop: Over 16.5 (-115)
National Football League odds courtesy of BetMGM. Odds updated Tuesday at 10:25 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
James Cook rushing stats and trendsCook collects 90 rushing yards per game this season, 19.5 more than Monday’s over/under.Three times this year (in five games – 60.0%), he rushed for more than 70.5 yards.Cook has had an average rushing yards prop bet set at 66.5 this season, which he’s out-gained on average by 23.5 yards.Cook has hit his rushing yards over in three of five opportunities (60.0% of his opportunities).He has multiple rushing TDs in one game this season. He’s hit paydirt on the ground in four total games.Bills vs. Falcons stats and trendsIn terms of defending against the run, the Falcons are 16th in the league, allowing 109 yards per game.The 135 passing yards the Falcons yield per game makes them the NFL’s best pass defense this season.The Bills have the seventh-ranked offense this season in terms of passing yards (241.4 passing yards per game), and they’ve been better on defense, ranking second-best with only 154 passing yards allowed per game.While the Bills rank fifth-worst in the NFL in rushing defense with 145.6 rushing yards allowed per game, it’s been a different situation offensively, as they rank second-best in the NFL (154.4 rushing yards per game).The Bills own the 15th-ranked defense this season in terms of yards per play (5.6 yards per play allowed), and they’ve been more effective on the other side of the ball, ranking fifth-best with 6.2 yards per play.
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