Star receiver Tyler Warren and the Indianapolis Colts (4-1) meet the Arizona Cardinals (2-3) on Sunday at 1 p.m. ET, at Lucas Oil Stadium.
The Colts enter this matchup after a 40-6 win over the Las Vegas Raiders in their last outing. The Cardinals’ most recent game ended in a 22-21 loss to the Tennessee Titans. Daniel Jones threw for 212 yards, with two touchdowns and no interceptions on 20-of-29 passing (69.0%) for the Colts in that matchup against the Raiders. Jonathan Taylor totaled 66 rushing yards on 17 carries (3.9 yards per carry), scoring three touchdowns on the ground. He also had three catches for 20 yards. Ashton Dulin had two receptions for 55 yards (27.5 per catch) against the Raiders. Kyler Murray’s performance for the Cards against the Titans included 23-of-31 passing for 220 yards, no touchdowns and no interceptions. He rushed four times for 25 yards and one touchdown. Emari Demercado put together a three-carry, 81-yard game (27.0 yards per attempt). Marvin Harrison Jr. recorded 98 yards through the air after four catches (on five targets).
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Colts vs. Cardinals game infoGame day: Sunday, October 12, 2025Game time: 1 p.m. ETLocation: Indianapolis, IndianaStadium: Lucas Oil StadiumTV channel: FOX (KMSB-Tuscon, AZ)Live stream: Fubo (Watch Now!)
Watch Indianapolis Colts vs. Arizona Cardinals on Fubo! (Regional restrictions may apply)
Colts vs. Cardinals betting info
NFL odds courtesy of BetMGM Sportsbook. Odds updated Friday at 3:05 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Colts (-7.5)Moneyline: Colts (-400), Cardinals (+310)Total: 47 points
Watch Indianapolis Colts vs. Arizona Cardinals on Fubo! (Regional restrictions may apply)