Before Kyler Murray and his teammates take the field Sunday at 1 p.m. ET on FOX, there will be numerous player prop bets available. Murray’s Arizona Cardinals (2-3) and the Indianapolis Colts (4-1) take the field in Week 6 at Lucas Oil Stadium.

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Kyler Murray week 6 player propsMatchup: Arizona Cardinals at Indianapolis ColtsTime: 1 p.m. ETDate: October 12, 2025Passing yards prop: Over 215.5 (-115)Rushing yards prop: Over 18.5 (-115)

National Football League odds courtesy of BetMGM. Odds updated Friday at 9:59 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Kyler Murray passing stats and trendsMurray’s passing yardage average this season (192.4) is 23.1 below Sunday’s over/under.In five games played this season, he has twice exceeded 215.5 passing yards in a single contest.Murray’s average prop bet for passing yards this season has been 219.7. His actual passing average is below that, by 27.3 yards per game.Murray has gone over his passing yards prop total once this season.He has thrown for a touchdown four times this year in five games played, including multiple TD passes twice.In two of five games this season, Murray has thrown an interception, with more than one INT on one occasion.Cardinals vs. Colts stats and trendsThe 217.0 passing yards the Colts allow per game makes them the NFL’s 19th-ranked pass defense this season.With 170.2 offensive passing yards per game (second-worst) and 254.2 passing yards allowed per game on defense (fifth-worst), the Cardinals have been playing poorly on both sides of the ball this season in the passing game.The Cardinals are totaling 118.2 rushing yards per game on offense this season (13th in NFL), and they are surrendering 92.4 rushing yards per game (eighth) on the defensive side of the ball.The Cardinals are surrendering 5.3 yards per play on the defensive side of the ball (seventh in the NFL), while gaining 5.2 per play (24th in the league) on offense this season.

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