Injuries have become even more prevalent around the NFL this season as several of the league biggest stars have missed significant amount of time. Lamar Jackson will miss his second straight game with the Baltimore Ravens (hamstring) while Brock Purdy is also out for the San Francisco 49ers (toe).

Those are the notable quarterbacks out for Week 6, while there is a notable starter that was a game-time decision. Arizona Cardinals quarterback Kyler Murray (foot) is officially inactive for Sunday’s game against the Colts. Quarterback Jacoby Brissett will start for Arizona, as it was trending that way all week. 

While Jackson is out for the Ravens, wide receiver Zay Flowers (shoulder) was questionable heading into the 1 p.m. games — but he will play. Cornerback Christian Gonzalez will also play for the Patriots while Anthony Richardson is a healthy scratch for the Colts as the QB2. Shedeur Sanders is active for the Browns as well.

Saints running back Alvin Kamara (ankle) was questionable, but he is not on the inactive report and will play. 

For the 4 p.m. games, Bengals wide receiver Ja’Marr Chase (illness) is questionable but expected to play. 49ers wide receiver Jauan Jennings (ankle/rib) is questionable. 

Keep it locked here for the latest injury updates for Sunday’s games.