The Buffalo Bills (4-1) play the Atlanta Falcons (2-2) on Monday, October 13, 2025 at Mercedes-Benz Stadium. The Bills are listed as favorites in this one, with the spread sitting at 3.5 points. The over/under for the contest is 50 points.

The Falcons’ last contest was versus the Washington Commanders, and they won by a score of 34-27.

In that game versus the Commanders, Dirty Birds quarterback Michael Penix Jr. completed 20 of 26 passes for 313 yards, with two touchdowns and one interception.

In their most recent game, the Bills lost versus the New England Patriots, 23-20.

Falcons vs Bills betting information

NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 9:47 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread favorite: Buffalo (-3.5)Moneyline: Buffalo (-206), Atlanta (+170)Total: 50 pointsFalcons betting insightsAtlanta was 4-5 overall, and 3-6 against the spread, at home last season.The Falcons have covered the spread two times this season (2-2-0).The Falcons are a perfect 1-0 ATS when playing as at least 3.5-point underdogs.In three of nine games at home last season, Atlanta hit the over.This season, Falcons games have hit the over once.Falcons leadersPenix: 918 PASS YDS / 229.5 YPG / 62.4% / 3 TD / 3 INTBijan Robinson: 64 CAR / 314 YDS / 78.5 YPG / 1 TD / 18 REC / 270 YDS / 67.5 YPG / 1 TDTyler Allgeier: 43 CAR / 155 YDS / 38.8 YPG / 2 TDDrake London: 24 REC / 269 YDS / 67.3 YPG / 1 TDKyle Pitts: 20 REC / 205 YDS / 51.3 YPG / 1 TDFalcons vs Bills game infoDate: Monday, October 13, 2025Time: 7:15 p.m. ETCity: Atlanta, GeorgiaVenue: Mercedes-Benz StadiumTV channel: ESPNLive stream: Watch on Fubo (Regional restrictions may apply)

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