Oddsmakers give the Denver Broncos (4-2) a good chance to keep their three-game winning streak intact, as they are favored by a touchdown in a matchup with the New York Giants (2-4) on Sunday, October 19, 2025 at Empower Field at Mile High.

Broncos vs. Giants game infoGame day: Sunday, October 19, 2025Game time: 4:05 p.m. ETTV channel: CBSLocation: Denver, ColoradoStadium: Empower Field at Mile HighLive stream: Watch this game on Fubo (Regional restrictions may apply)Live stream: Watch this game on Paramount+ (Regional restrictions may apply)

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Broncos vs. Giants odds & betting linesSpread favorite: Denver (-7)Moneyline: Denver (-361), New York (+286)Total: 40.5 points

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Broncos vs. Giants recent matchupsDenver has gone 2-1 versus New York over the last three matchups between the two teams.Denver outscored New York 68-56 in those three head-to-head matchups.Broncos vs. Giants betting insightsDenver, through six games with a spread so far this season, has gone 2-4-0 against the spread. The Broncos are 3-1 in the four games this season they have been favored on the moneyline. New York has three wins against the spread through six opportunities this season (3-3-0). The Giants will be moneyline underdogs for the seventh time this year. They are 2-4 as an underdog.Broncos scoring insightsThe Broncos’ scoring average at home, 24.0 points per game, is better than their average on the road, 20.5.On defense, Denver allows fewer points at home (7.5 per game) than away (20.0).The Broncos rank 24th in scoring offense over the last three contests (20.7 points per game), but they rank second-best in scoring defense over that stretch (10.3 points per game allowed).Giants scoring insightsAt home, the Giants are averaging more points (21.3) than on the road (19.0).Defensively, New York is giving up 19.0 points per game at home, better than its 29.0 average on the road.Offensively, the Giants are putting up 25.7 points per game in divisional matchups, which is better than their 14.7 average in non-division games.New York is allowing 26.0 points per game in divisional contests, which is higher than its 22.0 average in non-division games.In their past three games, the Giants are putting up 23.0 points per game (15th in NFL), and conceding 20.3 (eighth).Broncos injury reportBroncos:
Jonah Elliss: Did Not Participate In Practice (Shoulder),
Dre Greenlaw: Limited Participation in Practice (Quad),
Jonathon Cooper: Limited Participation in Practice (Quad),
Alex Singleton: Full Participation in Practice (Thumb),
Nik Bonitto: Full Participation in Practice (Wrist)Giants injury reportGiants:
D.J. Davidson: Did Not Participate In Practice (Knee),
Victor Dimukeje: Full Participation in Practice (Pectoral),
Roy Robertson-Harris: Limited Participation in Practice (Knee),
Jalin Hyatt: Limited Participation in Practice (Ankle),
Chauncey Golston: Did Not Participate In Practice (Neck),
Jermaine Eluemunor: Limited Participation in Practice (Shoulder),
Darius Slayton: Did Not Participate In Practice (Hamstring),
John Michael Schmitz: Did Not Participate In Practice (Concussion),
Demetrius Flannigan-Fowles: Did Not Participate In Practice (Hamstring),
Swayze Bozeman: Did Not Participate In Practice (Ankle),
Deonte Banks: Full Participation in Practice (NIR – Personal),
Dane Belton: Limited Participation in Practice (Neck),
Paulson Adebo: Limited Participation in Practice (Shoulder)

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