The Buffalo Bills are in the midst of their bye weekend off from action.

Doesn’t it always feel like it comes at the right time? It was for the Bills (4-2) in 2025.

Buffalo limps into their bye both physically and mentally. The team is fresh off of two-straight losses.

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What could heal both of those aspects is time off from football to heal some bumps and bruises. Prior to taking some time off, head coach Sean McDermott detailed some injury updates for players recently sidelined or who have missed an extended period during his last press conference before taking some time off himself.

Here’s the full rundown on those updates:

DT DaQuan JonesBuffalo Bills defensive tackle Daquan Jones tries to sack New England Patriots quarterback Drake Maye but May was able to get throw the ball for a completion during second half action at Highmark Stadium in Orchard Park on Oct. 5, 2025.

Buffalo Bills defensive tackle Daquan Jones tries to sack New England Patriots quarterback Drake Maye but May was able to get throw the ball for a completion during second half action at Highmark Stadium in Orchard Park on Oct. 5, 2025.

Injury: Calf.

Timeline: Week-to-week.

WR Josh PalmerATLANTA, GEORGIA - OCTOBER 13: Josh Palmer #5 of the Buffalo Bills makes a catch in the second quarter of the game against Dee Alford #20 of the Atlanta Falcons at Mercedes-Benz Stadium on October 13, 2025 in Atlanta, Georgia. (Photo by Kevin C. Cox/Getty Images)

ATLANTA, GEORGIA – OCTOBER 13: Josh Palmer #5 of the Buffalo Bills makes a catch in the second quarter of the game against Dee Alford #20 of the Atlanta Falcons at Mercedes-Benz Stadium on October 13, 2025 in Atlanta, Georgia. (Photo by Kevin C. Cox/Getty Images)

Injury: Ankle.

Timeline: Week-to-week.

LB Terrel BernardSep 18, 2025; Orchard Park, New York, USA; Buffalo Bills linebacker Terrel Bernard (8) runs against Miami Dolphins wide receiver Jaylen Waddle (17) in the fourth quarter at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images

Sep 18, 2025; Orchard Park, New York, USA; Buffalo Bills linebacker Terrel Bernard (8) runs against Miami Dolphins wide receiver Jaylen Waddle (17) in the fourth quarter at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images

Injury: Ankle.

Timeline: Day-to-day.

TE Dalton KincaidOct 22, 2023; Foxborough, Massachusetts, USA; Buffalo Bills tight end Dalton Kincaid (86) runs against New England Patriots cornerback J.C. Jackson (29) during the second half at Gillette Stadium. Mandatory Credit: Brian Fluharty-USA TODAY Sports

Oct 22, 2023; Foxborough, Massachusetts, USA; Buffalo Bills tight end Dalton Kincaid (86) runs against New England Patriots cornerback J.C. Jackson (29) during the second half at Gillette Stadium. Mandatory Credit: Brian Fluharty-USA TODAY Sports

Injury: Oblique.

Timeline: Day-to-day.

LB Matt MilanoORCHARD PARK, NEW YORK - OCTOBER 05: A.J. Epenesa #57 and Matt Milano #58 of the Buffalo Bills tackle Drake Maye #10 of the New England Patriots in the second quarter of the game at Highmark Stadium on October 05, 2025 in Orchard Park, New York. (Photo by Bryan M. Bennett/Getty Images)

ORCHARD PARK, NEW YORK – OCTOBER 05: A.J. Epenesa #57 and Matt Milano #58 of the Buffalo Bills tackle Drake Maye #10 of the New England Patriots in the second quarter of the game at Highmark Stadium on October 05, 2025 in Orchard Park, New York. (Photo by Bryan M. Bennett/Getty Images)

Injury: Pectoral.

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Timeline: Day-to-day.

WR Curtis SamuelOct 5, 2025; Orchard Park, New York, USA; Buffalo Bills wide receiver Curtis Samuel (1) scores a touchdown against the New England Patriots during the second half at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images

Oct 5, 2025; Orchard Park, New York, USA; Buffalo Bills wide receiver Curtis Samuel (1) scores a touchdown against the New England Patriots during the second half at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images

Injury: Ribs/neck.

Timeline: Day-to-day.

CB Maxwell Hairston (IR)Jun 11, 2025; Orchard Park, NY, USA; Buffalo Bills cornerback Maxwell Hairston (31) works out during Minicamp at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images

Jun 11, 2025; Orchard Park, NY, USA; Buffalo Bills cornerback Maxwell Hairston (31) works out during Minicamp at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images

Injury: Knee.

Timeline: Injured reserve; week-to-see.

This article originally appeared on Bills Wire: Sean McDermott: Bye week injury updates for the Buffalo Bills roster