The San Francisco 49ers (4-2) square off against the Atlanta Falcons (3-2) on Sunday, October 19, 2025 at Levi’s Stadium. The spread forecasts a close game, with the 49ers favored by 1.5 points. The over/under for the contest is 47.5 points.
Facing the Buffalo Bills in their most recent contest, the Falcons won 24-14.
The Dirty Birds’ Michael Penix Jr. was 20-for-32 for 250 yards against the Bills, with one TD and no INTs.
The 49ers lost against the Tampa Bay Buccaneers in their last game, 30-19.
Falcons vs 49ers betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 1:47 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: San Francisco (-1.5)Moneyline: San Francisco (-131), Atlanta (+110)Total: 47.5 pointsFalcons betting insightsAtlanta was 4-4 overall, and 3-4-1 against the spread, on the road last season.The Falcons have gone 3-2-0 against the spread this year.Atlanta had one win ATS (1-3) as 1.5-point underdogs or more away from home.The Falcons have an ATS record of 2-1 when playing as at least 1.5-point underdogs.In four of eight away games last season, Atlanta hit the over.Games involving the Falcons have hit the over once this season.Falcons leadersPenix: 1,168 PASS YDS / 233.6 YPG / 62.4% / 4 TD / 3 INTBijan Robinson: 83 CAR / 484 YDS / 96.8 YPG / 2 TD / 24 REC / 338 YDS / 67.6 YPG / 1 TDTyler Allgeier: 53 CAR / 187 YDS / 37.4 YPG / 3 TD / 3 REC / 10 YDS / 2 YPG / 0 TDDrake London: 34 REC / 427 YDS / 85.4 YPG / 2 TDKyle Pitts: 23 REC / 223 YDS / 44.6 YPG / 1 TDFalcons vs 49ers game infoDate: Sunday, October 19, 2025Time: 8:20 p.m. ETCity: Santa Clara, CaliforniaVenue: Levi’s StadiumTV channel: NBCLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Peacock
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