Christian McCaffrey and the San Francisco 49ers (4-2) will host Bijan Robinson and the Atlanta Falcons (3-2) on Sunday at 8:20 p.m. ET, in a matchup between two outstanding runners.
The Falcons are generating 20 points per contest on offense this season (27th-ranked). Meanwhile, they are surrendering 20 points per game (seventh-ranked) on defense. The 49ers are averaging 373.7 yards per game on offense (sixth in NFL), and they rank 15th defensively with 321.7 yards allowed per game.
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Falcons vs 49ers: Live streaming info, TV channel & game timeGame day: Sunday, October 19, 2025Game time: 8:20 p.m. ETLocation: Santa Clara, CaliforniaStadium: Levi’s StadiumTV channel: NBCLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Peacock!
Watch San Francisco 49ers vs. Atlanta Falcons on Fubo! (Regional restrictions may apply)
Falcons vs 49ers betting lines
NFL odds courtesy of BetMGM. Odds updated Sunday at 12:14 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: 49ers (-1.5)Moneyline: 49ers (-129), Falcons (+108)Total: 47.5 points
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