The Atlanta Falcons (3-2) will look to upset the San Francisco 49ers (4-2) on Sunday, October 19, 2025 at Levi’s Stadium. The spread foretells a close game, with the 49ers favored by 1.5 points. The over/under in the contest is set at 47.5 points.
Against the Tampa Bay Buccaneers in their last game, the 49ers lost 30-19.
Niners quarterback Mac Jones went 27-for-39 for 347 yards, with no TDs and two INTs, against the Buccaneers.
The Falcons’ last contest was against the Buffalo Bills, and they won by a score of 24-14.
49ers vs Falcons betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 12:47 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: San Francisco (-1.5)Moneyline: San Francisco (-129), Atlanta (+108)Total: 47.5 points49ers betting insightsAt home last season, San Francisco was 4-5 overall and 4-5 against the spread.The 49ers have covered the spread three times in six games with a set spread.Last year, as 1.5-point favorites or greater at home, San Francisco was 4-4 ATS.In games they have played as 1.5-point favorites or more, the 49ers have an ATS record of 2-2.Last season, San Francisco hit the over in five of nine games at home.49ers games have gone over the total four times this season.49ers leadersJones: 1,252 PASS YDS / 313 YPG / 67.3% / 6 TD / 3 INTChristian McCaffrey: 108 CAR / 336 YDS / 56 YPG / 1 TD / 46 REC / 444 YDS / 74 YPG / 3 TDBrian Robinson Jr.: 27 CAR / 108 YDS / 18 YPG / 0 TD / 5 REC / 11 YDS / 1.8 YPG / 0 TDKendrick Bourne: 23 REC / 371 YDS / 74.2 YPG / 0 TDRicky Pearsall: 20 REC / 327 YDS / 81.8 YPG / 0 TD49ers vs Falcons game infoDate: Sunday, October 19, 2025Time: 8:20 p.m. ETCity: Santa Clara, CaliforniaVenue: Levi’s StadiumTV channel: NBCLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Peacock
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